Enabling Cell Line Selection, Process Characterization and Process Optimization in a Quick and Efficient Way
Comparing cultures in identically-sized, multi-parallel bioreactors allow scientists to find out more process information in a shorter timeline. Multiple experiments can be set up to evaluate different culture strains and the effect of process parameters, such as temperature, feeding, media composition, gassing rates and inoculation densities.
The industry-leading range of ambr® multi-parallel bioreactors has been developed to take you through the early steps of your upstream process from cell or strain selection, through to process optimization. The technology ensures optimum scalability of your processes, as the design of the bioreactors means that functionality translates well into systems such as the BIOSTAT STR® 2000 and larger.
High Throughput Bioprocess Development
Kistler, Pollard, Lee, Streefland (2016) Genetic Engineering & Biotechnology News (Vol. 36, No. 7) Apr 2016
Bioprocess engineers are achieving better process understanding and more optimal cell culture conditions by using high throughput scale-down methods and design of experiment (DOE) approaches.
This bioprocessing tutorial explains how process development scientists can use the ambr® 250 automated bioreactor system to screen a wide process design space, while minimizing resources and materials.