Add-On Capability for pH Calibration and Raman Spectroscopy for Ambr® Bioreactors

The Analysis Module provides add-on capability for at-line measurement of pH and optionally, Raman spectroscopy, for Ambr® 15 and Ambr® 250 High Throughput bioreactors. The pH measurement automates initial bioreactor vessel pH sensor calibration and subsequent in-process re-calibration, eliminating the operator time needed for manual offline pH measurement, data transfer, and bioreactor pH sensor recalibration.

Ambr® Analysis Module Benefits

  • Full automation of pH measurement sampling and assay
  • Reduced CO₂ outgassing effects and errors compared to manual off-line pH sampling
  • Automated accurate pH sensor recalibration
  • Optimised pH measurement modes for normal and high cell density cultures
  • Allows integration of 3rd party Raman spectroscopy probes and data flows

Ambr® Analysis Module

  • Provides pH measurement and Raman Spectroscopy for Ambr bioreactors
  • Enables matching of pH measurement and cell culture temperature
  • Tracking of pH electrode performance over time
  • User replaceable pH sensors, Raman flow cells, and reagent kits
  • Reagent kits including calibration solutions, cleaning solutions and a waste container

You can use the Ambr® analysis module together with:

Ambr® 15 Cell Culture

Ambr® 250 High Throughput

Ambr® 250 High Throughput Perfusion

The Ambr® Analysis Module is suitable for use with both cell culture and microbial media and supports measurement approaches for cell cultures up to at least 100 million cells/ml. It is not suitable for cultures containing particulates (beads or microcarriers, for example) or highly viscous samples.

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Ambr® Analysis Module Downloads


Ambr® Analysis Module - pH Calibration and Raman Spectroscopy Integration

PDF | 3.1 MB

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