Add-On Capability for pH Calibration and Raman Spectroscopy for ambr® Bioreactors

The analysis module provides add-on capability for at-line measurement of pH and optionally, Raman spectroscopy, for ambr® 15 and ambr® 250 high throughput bioreactors. The pH measurement automates initial bioreactor vessel pH sensor calibration and subsequent in-process re-calibration, eliminating the operator time needed for manual offline pH measurement, data transfer and bioreactor pH sensor recalibration.

Operation of the analysis module is supported by user replaceable sensors (electrodes) and reagent kits including calibration solutions, cleaning solutions and a waste container. analysis module is suitable for use with both cell culture and microbial media. analysis module is not suitable for use with particulates (for example microcarriers will block internal tubing) or highly viscous cultures or samples (e.g. filamentous microbes).

You can use the ambr® analysis module together with:

ambr® 15 cell culture

ambr® 15 fermentation

ambr® 250 high throughput

ambr® 250 high throughput perfusion

The analysis module is suitable for use with both cell culture and microbial media, however is unsuitable for particulates, highly viscous sample or high cell density perfusion cultures.

ambr® analysis module

  • Frequent, accurate pH sensor recalibration
  • Enables full automation of sample handling and assay read
  • Enables measurement temperature to match the culture temperature
  • Reduces CO2 outgassing effects and errors compared to manual offline samples

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ambr® analysis module Downloads

Brochure: ambr® analysis module - pH Calibration and Raman Spectroscopy Integration

PDF | 1.3 MB