Ambr® 250 Modular

Increased Productivity with Simplified Operation

Ambr® 250 Modular is an innovative, easy-to-use, expandable benchtop system that incorporates from 2 to 8 fully integrated single-use 100 – 250 mL mini bioreactors.

It has a wide range of applications in:

  • Process optimization
  • Process characterization


Ambr® 250 Modular Overview

This video shows how the expandable nature of the Ambr® 250 Modular system makes it easy to operate from experiment setup and through sampling and data analysis.

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Ambr® 250 Modular Consumables 

Get your Ambr® 250 consumables in time for your next experimental run.

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Ambr® 250 Modular Vessel for Cell and Gene Therapies

The new unbaffled vessel design has a large pitched blade impeller and a working volume of 100-250 mL.

It provides an environment for gentle agitation and mixing without sedimentation, allowing optimal growth of single cell suspensions, cell aggregates or adherent cells on microcarriers.

In trials with leading cell and gene therapy companies, the new mini bioreactor has shown better cell culture performance compared with less predictive spinner or T-flask models, enabling rapid process optimization and improved scalability to larger bioreactors.

The vessel is suitable for:

  • Rapid process development and process optimization
  • HEK293, CAR-T and other therapeutic cell lines
  • Other cultures requiring specialized mixing at slower impeller speed

Ambr® 250 Bibliography

Find out more about processes conducted in Ambr® 250 systems. The bibliography lists publications by phase in the process stream.

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Featured Assets

Application Note

T Cell Expansion for Cellular Immunotherapy

In this application note, we demonstrate the expansion of CAR-T cells in the Ambr® 250 Modular system.

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Application Note

Anaerobic Cultivation and Spore Formation of Clostridium Sporogenes

Find out how the Ambr® 250 Modular system can be used to optimize cell growth and spore formation of the anaerobe Clostridium sporogenes.

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Application Note

Optimize and Scale Up Production of Human IPSC

This application note describes how Sartorius systems were used to create a scalable platform for iPSC production.

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Related Assets

Brochures

Brochure

Ambr® 250 Modular - Consumables and Accessories

PDF | 4.3 MB
Brochure

Ambr® 250 Modular - Simplified Operation for Increased Productivity

PDF | 4.3 MB
Technical Note

Ambr® 250 Modular: Technical Specification

PDF | 2.4 MB

Posters

Poster

Superior Scalability of a Single-Use BioreactorFamily from 0.25 to 2000 L

PDF | 1.1 MB
Poster

Evaluation of a Stirred Small Scale Single-Use Bioreactor for Microbial Application

PDF | 2.3 MB
Poster

Upstream Microbial Process Characterizationwith Single-Use Bioreactors from 250 mL to 50 L

PDF | 2.0 MB
Poster

Optimizing T Cell Expansion in Ambr® 15 Cell Culture UsingDoE and Process Transfer to Ambr® 250 Modular

PDF | 2.7 MB

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