Laboratory Filtration and Purification

Sartorius offers an extensive range of laboratory filtration and purification solutions, from basic filters and holders, to class-leading vacuum, syringe and crossflow filters, and resin-free chromatography consumables. Each of our products is designed to help you achieve accurate, reproducible results, through simplified workflows that ensure efficiency in every step of your separation workflows.

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Clarification Filters

Streamline your sample prep with Sartolab® RF|BT and Sartoclear Dynamics® Lab filtration systems.

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In-Line Filters

Discover the Sartolab® P20 filters as ultimate solution for efficient, high-volume filtration with unmatched versatility and reliability.

Application photo showing the Vivaflow SU system set up for ultrafiltration on a laboratory bench

Ultrafiltration

Ultimate solutions including Vivaspin® and Vivaflow®, offering the flexibility to rapidly concentrate and rebuffer any molecule.

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Lab Chromatography 

Purify antibodies, viruses and other biomolecules faster, on process-ready Sartobind® membranes.

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Syringe Filters

Minisart® syringe filters provide top-quality, reliable filtration with highest surface areas.

Syringeless Filters

Improve user ergonomics and sustainability through the removal of plastic syringes with the Claristep® filter station.

Glass & Quartz Microfiber Filters

Specialized filter matrices offer highly-versatile, fast-flowing and chemically robust filtration for a wide range of demanding applications.

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Membrane Filters

As the first industrial membrane manufacturers, we have been offering membrane and membrane accessory excellence since 1927.

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Filters & Blotting Papers

Discover Sartorius' high-performance membranes and papers for superior blotting results.

Applications for Lab Filtration & Purification

Featured Lab Filtration & Purification Applications

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Sterile Filtration

Sample sterilization with our 0.2µm membrane filtration products abides by the validated Bacterial Challenge Test according to ASTM F838 standards

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Cell Harvesting

To enable rapid clarification and sterile filtration of 15 mL to 1,000 mL cell culture samples in one step, eliminating the need for centrifugation.

Application photo showing the Vivaflow SU system set up for diafiltration on a laboratory bench

Buffer Exchange

Buffer exchange solutions from Sartorius use ultrafiltration as the method of choice, thanks to its flexibility, speed, and lower buffer consumption

Particle Analysis 

Find a range of membrane and technical papers, especially chemically robust quartz microfiber filters, which provide purity and strength.

More Lab Filtration & Purification Applications

Clinical Diagnostics

Measurement and detection of certain proteins and disease markers from clinical samples plays an important part in the diagnosis and monitoring of diseases and disorders. A variety of ultrafiltration products are available for clinicians to isolate and concentrate disease markers for further analysis, using static, pressure or centrifugal product designs. 

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Drug Discovery

Boost productivity and find the most promising candidates sooner with efficient separation of your drug candidate from cells, cell debris and unwanted host cell proteins and other molecules. Ensure optimal recovery of your candidates without impacting characterization or functionality. Our innovative, high-quality devices will provide high-resolution separation throughout the clarification, concentration, purification and sterile filtration workflow. 

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Sample Preparation

In a range of applications, removal of sample particulates and contaminating molecules — prior to analytics — is crucial for accurate and precise results. Our filters are HPLC and analytics-ready with a variety of certificates and extractables and leachables data. Membrane material is chosen for its low molecule adsorption and low dead volumes, to further increase reliability of results. 

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Sartorius Lab Filtration and Purification Products are Supported By:

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Extensive Application Resources

Access an extensive range of filtration and purification application notes and white papers that provide optimization guidance, application results and case studies. 

Detailed Technical Guides

Lean on a wide range of lab filtration and purification product technical guides to support your selection and best practice uses.

Product Demonstrations & Sampling

Confirm which lab filtration and purification product is best for your application and learn methods for optimization with demonstrations and sample packs.


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A Range of Certifications

To support your quality and compliance requirements, Sartorius provides a range of lab filtration and purification product and quality certifications.    

Lab Filtration & Purification Resources

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Infographic

Advancing Antibody Purification With Essential Lab Equipment

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Cell Therapy CAR-T cell attacking cancer cell
Poster

Lab-Scale Tools for Advanced LV Downstream Processing

This study presents a complete lab-scale DSP workflow for clarifying, purifying, concentrating LVs produced in suspension HEK cell culture.

Webinar

Optimizing Diagnostic Sample Preparation Workflows With Ultrafiltratio...

Learn practical strategies to improve your diagnostic sample preparation workflows and diagnostic kit reliability in this on-demand webinar.

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Resource Guide

Lab Filtration Catalogue 

Providing a comprehensive overview of our laboratory filtration products and solution, with technical information and product specifications.

Blog

Lab Separation: 5 Tips for Choosing Your Ideal System

From basic research to environmental and clinical testing, filtration and purification are core laboratory techniques. Read the five tips. 

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Get answers to any questions you have about Sartorius lab filtration and chromatography products.

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Lab Filtration & Purification FAQs

Laboratory filtration is the physical or mechanical separation of particles or components within a sample medium such as a liquid or gas by introducing a medium through which only the gas/liquid can pass. Therefore a size exclusion that will separate the starting sample into two fractions. One fraction (permeate/filtrate) will be the clarified/filtered sample, which contains only particles or molecules that are small enough to pass through the filter medium. The second fraction (retentate/concentrate) is the sample material that has been retained by the filter medium, this fraction may often be solid as all liquid sample has passed through the filter.

Consider the following when choosing a lab filter: 

  • What volume will be filtered?
  • What is your goal? Is it to remove contaminants or concentrate the target? 
  • What is the size of the contaminants and target(s)? 
  • Is sterility needed? 
  • Do I need vacuum, pressure, syringe, peristaltic or other method of action?

Once these points are established, product selection can begin. 
 

Filtration processes can be separated according to mode of action or force behind the separation, e.g. pressure, vacuum, centrifugal, tangential flow filtration (cross flow filtration). 

The capacity or throughput of a filter depends on many characteristics such as sample composition and particle load, operating temperature, and the filter area, pore size and porosity. For most Sartorius laboratory filters, you will find a typical capacity or volume range listed in the technical specifications.

Most laboratory filters use relatively small membrane areas and therefore, to ensure the best filtration performance, are intended for single use. When reusability is important, Sartorius also offers selected filters and holders that enable some parts or an entire unit to be used multiple times. The number of times that these products can be used is dependent on several factors including sample composition, effectiveness of cleaning, and proper storage.

Online literature, papers and research forums are a good source of application information. However, for specific advice on filtration methods across a range of application workflows, Sartorius has an extensive range of test data, technical guides and application notes and are available to contact for advice and workflow queries. Further, product samples or demonstrations are often available free of charge to help users confirm the optimal lab filtration processes.

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