Laboratory Filtration and Purification
Sartorius offers an extensive range of laboratory filtration and purification solutions, from basic filters and holders, to class-leading vacuum, syringe and crossflow filters, and resin-free chromatography consumables. Each of our products is designed to help you achieve accurate, reproducible results, through simplified workflows that ensure efficiency in every step of your separation workflows.
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Applications for Lab Filtration & Purification
Featured Lab Filtration & Purification Applications
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Clinical Diagnostics
Measurement and detection of certain proteins and disease markers from clinical samples plays an important part in the diagnosis and monitoring of diseases and disorders. A variety of ultrafiltration products are available for clinicians to isolate and concentrate disease markers for further analysis, using static, pressure or centrifugal product designs.
Drug Discovery
Boost productivity and find the most promising candidates sooner with efficient separation of your drug candidate from cells, cell debris and unwanted host cell proteins and other molecules. Ensure optimal recovery of your candidates without impacting characterization or functionality. Our innovative, high-quality devices will provide high-resolution separation throughout the clarification, concentration, purification and sterile filtration workflow.
Sample Preparation
In a range of applications, removal of sample particulates and contaminating molecules — prior to analytics — is crucial for accurate and precise results. Our filters are HPLC and analytics-ready with a variety of certificates and extractables and leachables data. Membrane material is chosen for its low molecule adsorption and low dead volumes, to further increase reliability of results.
Sartorius Lab Filtration and Purification Products are Supported By:
Access an extensive range of filtration and purification application notes and white papers that provide optimization guidance, application results and case studies.
Lean on a wide range of lab filtration and purification product technical guides to support your selection and best practice uses.
Confirm which lab filtration and purification product is best for your application and learn methods for optimization with demonstrations and sample packs.
To support your quality and compliance requirements, Sartorius provides a range of lab filtration and purification product and quality certifications.
Lab Filtration & Purification FAQs
Laboratory filtration is the physical or mechanical separation of particles or components within a sample medium such as a liquid or gas by introducing a medium through which only the gas/liquid can pass. Therefore a size exclusion that will separate the starting sample into two fractions. One fraction (permeate/filtrate) will be the clarified/filtered sample, which contains only particles or molecules that are small enough to pass through the filter medium. The second fraction (retentate/concentrate) is the sample material that has been retained by the filter medium, this fraction may often be solid as all liquid sample has passed through the filter.
Consider the following when choosing a lab filter:
- What volume will be filtered?
- What is your goal? Is it to remove contaminants or concentrate the target?
- What is the size of the contaminants and target(s)?
- Is sterility needed?
- Do I need vacuum, pressure, syringe, peristaltic or other method of action?
Once these points are established, product selection can begin.
Filtration processes can be separated according to mode of action or force behind the separation, e.g. pressure, vacuum, centrifugal, tangential flow filtration (cross flow filtration).
The capacity or throughput of a filter depends on many characteristics such as sample composition and particle load, operating temperature, and the filter area, pore size and porosity. For most Sartorius laboratory filters, you will find a typical capacity or volume range listed in the technical specifications.
Most laboratory filters use relatively small membrane areas and therefore, to ensure the best filtration performance, are intended for single use. When reusability is important, Sartorius also offers selected filters and holders that enable some parts or an entire unit to be used multiple times. The number of times that these products can be used is dependent on several factors including sample composition, effectiveness of cleaning, and proper storage.
Online literature, papers and research forums are a good source of application information. However, for specific advice on filtration methods across a range of application workflows, Sartorius has an extensive range of test data, technical guides and application notes and are available to contact for advice and workflow queries. Further, product samples or demonstrations are often available free of charge to help users confirm the optimal lab filtration processes.