Cell Harvesting Solutions by Sartorius

Sartoclear Dynamics® Lab — Convenient Mammalian Cell Culture Harvesting

Sartoclear Dynamics® Lab kits are designed for rapid harvesting 15 mL to 1,000 mL volumes of cell cultures in the lab, enabling clarification and sterile filtration to be performed in one step. These kits simplify the process by fully eliminating the centrifugation step otherwise needed for clarification. As a result, up to 1,000 mL cell cultures can be efficiently clarified and sterilized in minutes – quickly and easily.

Product Portfolio

Sartoclear Dynamics® Lab Filtration Kits

Sartoclear Dynamics Lab clarifies high-density mammalian cell cultures faster and more efficiently than other processes.
Watch this comparison video.

Buy Kits Now

Sartoclear Dynamics® Lab V Kits

Clarification and sterile filtration of up to 1 L mammalian  cell culture combining a filter aid for clarification and a vacuum filtration unit for sterile filtration.

  • Sterilized pouches of filter aid and vacuum filtration units
  • 14 kits to cover a range of sample volumes up to 1,000 mL with cell densities up to 20 x 106 cells/mL

Buy Kits Now

Sartolab® Multistation for Hands-Free Filtration of Small Volumes

For simultaneous filtration of up to 6 x 50 mL samples without the need for installation of extra connectors and time-consuming stabilization of filter units. 

  • Hands-free filtration
  • One single vacuum source enables simultaneous filtration of up to 6 samples
  • Time-saving - no installation time for each filter unit before use

See Product Details & Request a Quote

Sartoclear Dynamics® Lab P15 Kit 

Convenient, ready-to-use-kit combines a 20 mL syringe pre-filled with a filter aid for clarification with a 0.2 um polyethersulfone filter for sterile filtration.

  • One filtration kit designed for all cell densities

See Product Details & Request a Quote

Sartoclear Dynamics® Lab and Multistation in Action 

LifeArc Testimonial

The team at LifeArc, a medical research charity based in the UK, is using the Sartoclear Dynamics®️ Lab and Sartolab®️ Multistation to clarify high-density cell culture media in minutes, creating a workflow that’s more efficient and productive.

"Processing mammalian cell culture fluid can be particularly challenging, as in the lab we are often driven by the need to perform this task quickly with minimum loss in the quantity of cell culture fluid obtained. Standard vacuum filtration isn’t always the ideal solution due to limitations in the sophistication of the equipment itself. It often requires additional supervision and can be quite time-consuming to undertake, particularly when there are several samples involved.

The Multistation has significantly helped our lab.  In addition to the six-sample capacity, the independently controlled multi-port design has provided operators with the flexibility to perform additional tasks in parallel, thereby delivering greater efficiency overall in the lab with improved cell culture fluid harvesting."

- Richard Brown, BSc, Scientist at LifeArc


Sirion Biotech GmbH

The team at Sirion Biotech GmbH, a leading viral vector manufacturer based in Germany, is using the Sartoclear Dynamics®️ Lab and Multistation to achieve clarification within minutes while simultaneously filtering up to 6 L, significantly accelerating their upstream processes.

"As a leading viral-vector manufacturer, we strive to produce the highest quality rAAVs in the shortest possible time. Isolating rAAVs from crude cell-lysates typically requires centrifugation and/or PEG precipitation – steps which are time consuming, labor intensive and generate a lot of plastic waste. The single-use Sartoclear Dynamics® Lab Filter kits has enabled us to streamline our upstream processes. The crude-lysates are directly filtered over Sartoclear Dynamics® Lab Filter kits. Clarification is achieved within a few minutes and the Multistation set-up allows us to simultaneously filter up to 6 L. The rAAV-recoveries using Sartoclear Dynamics® Lab products are remarkably high, surpassing what we obtain using in-depth filtration. Moreover, lysates clarified using Sartoclear Dynamics® Lab are instantly ready for our downstream processes including affinity capture by FPLC. Sartoclear Dynamics® Lab, along with the Multistation, have greatly improved our workflow."

- Kimchi Strasser, PhD., Team Lead for Process Development at Sirion Biotech GmbH (a Perkin Elmer company)

Lab Filtration & Purification Resources

Browse All Resources

Application Notes

Cover image of Clarification of Large-Volume Bacterial Cultures App Note
Application Note

Centrifuge-Free Clarification of Large-Volume Bacterial Cultures

Sartoclear Dynamics®️ Lab protocol for the production of large volumes of cell-free bacterial isolates without centrifugation

Access the App Note
Application Note

Reducing Sample Preparation Time from Sf9 Insect Cultures

In this study, the Sartoclear Dynamics® Lab V500 Kit was tested as a novel method for the clarification of cell culture media prior to purification of...

Access the App Note
Application Note

Mammalian Suspension Cultures App Note

This study evaluates a novel method for lab-scale clarification of mammalian cell culture supernatants. 

Access the App Note
Application Note

Mammalian Cell Cultures to Pure Proteins

The novel Sartoclear Dynamics® Lab V Kit was evaluated for the removal of transiently IgG expressing mammalian MEXi-293E (HEK293) cells from cell...

Access the App Note
Application Note

Rapid Mammalian Cell Harvest without Centrifugation

In this study, we describe our tests of Sartoclear Dynamics® Lab V, a novel system for rapid clarification of cell culture media without the need...

Access the App Note
Application Note

Centrifuge Free Clarification of Antibodies

Clarification of 50 mL suspension adapted HEK-293-6E cells, transiently expressing human IgG4 by comparing a conventional harvest method and the Sarto...

Access the App Note
Application Note

Lab-Scale Harvest and Clarification of Lentiviral Vectors

In this study, the use of Sartoclear Dynamics®️ Lab V50 comprising the diatomaceous earth filter aid was evaluated for clarification of lentiviral vec...

Access the App Note
Application Note

Centrifuge Free Clarification and Harvest of AA Viruses

This study aimed to evaluate the applicability of Sartoclear Dynamics® Lab Filter Aid.

Access the App Note

Product Resources

Sartoclear Dynamics Lab brochure

Sartoclear Dynamics® Lab Convenient Mammalian Cell Culture Harvesting

PDF | 3.3 MB

Request a Quote, Demo, or More Information

What other areas are you interested in? (select all that apply)

Request a Sample, Trial, Demo, Quote, or More Information

Ready to Buy?