mAb Molecule Development — Target Identification/Validation

Target Identification/Validation

Molecule development begins with target identification and validation. A new drug starts as an idea or hypothesis based on

  • Observations made during phenotypic drug discovery evaluations, or
  • Direct identification of targets with affinity during target-based drug discovery processes

Both these approaches require comprehensive understanding of the biological and molecular pathways underlying disease.

See how our IncuCyte® Live-Cell Analysis and Intellicyt® iQue3 platforms can accelerate your mAb discovery workflow!

Contact us

NEW INFOGRAPHIC

Challenges and Solutions for Developing New Monoclonal Antibodies

Unprecedented advances in medicine are delivering remarkable results for some patients. Recent approvals of CAR T therapies and new approaches in regenerative medicine, for example, exemplify Monoclonal antibodies (mAbs) used for immunotherapy stimulate the immune system to mount a response to target antigens. These powerful therapeutics are being used to...

Download to learn more

WEBINAR

Accelerating Nanobody Discovery Workflows with High-Throughput Flow Cytometry

In this webinar, Dr. Pieter Kennis discusses how nanobodies – small, single-domain antibody fragments that retain full antigen-binding capabilities and the properties of heavy-chain antibodies – and nanobody discovery and screening platforms exploit high-throughput flow cytometry to increase the throughput of nanobody screening campaigns.

Register to Watch Now

IncuCyte® Live-Cell Analysis System

Don't miss crucial data by analyzing cells at pre-determined time points. Continuously interrogate dynamic changes in the same population of cells using imaged-based, real-time, live-cell analysis for relevant insight to cell- and treatment-specific responses – all from inside your incubator.

Learn more

Intellicyt® iQue3

Advance therapeutic antibody discovery with multiplexed screening. The Intellicyt iQue3 offers high content, multi-factorial, and actionable results for more insight and better decisions.

Learn more

Resources

Brochure: Intellicyt® iQue3 Faster, Smarter Flow Cytometry

PDF | 6.0 MB

Download

Application Note: Minimizing Syringe Filter Usage in harvesting Monoclonal Antibodies from CHO Cell Culture Supernatants

PDF | 204.5 KB

Download

Application Note: Vivaflow® 200: A Critical Sample Preparation Tool for Concentrating Hybridoma Supernatants

PDF | 680.9 KB

Download

Application Note: Concentration of Mammalian Cell Culture Supernatants with Vivaspin® Turbo 15 and Amicon® Ultra-15 Devices

PDF | 138.5 KB

Download

Request More Information

Are you interested in the following cell analysis instruments for your research?

Other areas of interest? (Please check all that apply)

How can we assist you?