Scientist viewing BLI detection information for Octet RH96 in a laboratory.

Label-Free Detection

Overview of Label-Free Biomolecular Interaction Analysis

Welcome to Sartorius' advanced platform for label-free biomolecular interaction analysis. 

Label-free detection (also label-free (LF) technology, label-free analysis, or label-free sensing) utilizes optics-based biosensors. Our approach, featuring Biolayer Interferometry (BLI) and Surface Plasmon Resonance (SPR) technology, enables precise, real-time monitoring of analyte-ligand interactions without the interference of detection labels preserving the ligand's native conformation and providing insights that are more physiologically relevant. 

Our label-free platform facilitates comprehensive kinetic and affinity analyses, or simple concentration determination from analyte titer to residue analysis to characterizing multiple critical quality attributes (CQAs) in a single sample. Elevate your research in drug discovery and protein characterization with Sartorius' advanced label-free detection solutions.

Applications for Label-free Biomolecular Interaction Analysis

Simplifying Progress

T cell releases antibodies, binding to virus

Protein-Protein Interactions

Understanding PPIs is fundamental to advancing research in cell biology and drug development.

Gene Therapy Development

Experience novel, rapid, and high-throughput approaches for determining AAV titer and empty/full ratio.

Find Out How You Can Leverage the Power of Octet®️

Boost your research and commercialization goals by combining BLI and SPR at an attractive promotional price. 

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