Label-Free Detection

Applications for Label-Free Detection

Label-free assays convert biological responses into signals without the use of a fluorescent label.  They are heavily applied in kinetics analysis to determine rates of binding in receptor-ligand binding analysis and in detecting the presence and concentration of biological molecules.

The Sartorius Octet and Pioneer family of instruments provides real-time measurements in the analysis of therapeutic biological molecules at different stages of development. With unparalleled ease of use, the Octet and Pioneer family of instruments moves your workflow beyond the limitations of existing label-free methods. You get comprehensive characterization across a broad range of applications that are critical for efficient development and production.

With a wide range of ligand capture surfaces that allow for the immobilization of antibodies, recombinant proteins, DNA, RNA and virus like particles, the Octet platform has become a must have laboratory tool for a broad range of biomolecular interactions studies.  The Pioneer platform is a high sensitivity system for improved biophysical characterization of small molecule-protein interactions and streamlined fragment screening campaigns.

Label-Free Detection at a Glance

Affinity & Kinetic Characterization

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Biologics & Small Molecules Research

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COVID-19 Research & the Octet Platform

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GxP Applications

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Lead Selection & Optimization

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Target ID & Validation

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Titer & Impurity Testing

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Discover Sartorius Solutions for Protein Analysis

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