Idea-to-Lead: Advances in Discovery & Characterization of Therapeutic Antibodies eBook
Last updated: March 2023
Overview
Monoclonal antibodies (mAbs) are one of the fastest-growing classes of biopharmaceuticals and represent highly successful treatment strategies for a broadening range of autoimmune, inflammatory, infectious, and immuno-oncology diseases. However, despite technological and methodological advancements, developing new mAbs can be time-consuming and cumbersome.
In this eBook, you’ll discover how advances are being made in the discovery and characterization of therapeutic antibodies using the latest antibody screening tools from Sartorius - Incucyte® Live-Cell Analysis, iQue® Advanced Flow Cytometry, and Octet® BLI Label-Free Detection.
This expert guide includes how these tools can be leveraged to comprehensively assess novel mAbs, improve the identification and qualification of hits during screening, and accelerate and simplify drug discovery workflows.
- Document type: eBook
- Page count: 85
- Read time: 2 hours 38 minutes
Key Takeaways
- High-throughput mAb characterization
- Real-time kinetic insights into antibody function
- Use of advanced flow cytometry to accelerate antibody screening
- Multiparametric analysis of cell health, viability, phenotype, and effector function
- Antibody, small molecule, and phenotypic screening
- Combining advanced flow cytometry and live-cell imaging for antibody profiling
- The rise of label-free technologies
- Determining antibody titer in hybridoma samples
Figure 1. eBook Cover