Biologics Characterization Tools

Industry Standards for Label-Free Analysis of Biomolecular Interactions

The Sartorius Octet® platforms consist of label-free instruments based on Bio-Layer Interferometry (BLI) and Surface Plasmon Resonance (SPR) technologies, both of which are included within United States Pharmacopeia (USP) chapters as appropriate for bioanalytical analysis.  The Octet® family of instruments have been an industry standard for label-free analysis across biologics development and manufacturing for over 15 years.

From drug discovery through development to manufacturing, BLI and SPR characterization of biologics provides critical information on binding specificity, affinity, and kinetics of biomolecular interactions. Octet® BLI assays are ideal for titer and concentration analysis and screen for Critical Quality Attributes early in cell line development and bioprocess development workflows.

Octet® systems have been widely used in the biopharma industry and academic research, covering the span from small molecule fragments to antibodies and recombinant proteins to whole virus particles.

Sartorius Solutions for Biologics Characterization

Octet Label-Free Detection Systems

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OneStep SPR Systems

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Octet Systems Software

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GxP Compliance

GxP Compliance Tools

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Octet biosensors

Biosensors & Kits

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Why Choose Sartorius for Biologics Characterization Tools?

Continuous Innovation

As a trusted scientific partner, we deliver unique solutions to research challenges by providing best-in-class products for real-time analysis of biomolecular interactions in micro-volume sample sizes, providing information on affinity, kinetics, and concentration.

Extensive Publication Success

Sartorius systems have become indispensable tools in academic and biopharmaceutical research, from characterizing binding interactions and specificity to engineering proteins and antibodies. We have over 5000 publications from the use of Octet® products within various applications.

World Class Service

Our comprehensive service plans include validation, system qualification and preventative maintenance that reduce operating costs and maximize lab productivity. Our experienced team of technical support, FAS and applications development scientists are always available to consult with you on your research.

Featured Products for Biologics Characterization

2-Channel System: Octet® R2

Grows With Your Biomolecule Characterization Needs

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4-Channel System: Octet® R4

The Perfect Balance Between Cost and Throughput with Given Leeway

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8-Channel System: Octet® R8

Unmatched Flexibility and Versatility in Protein Analysis

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16-Channel High Throughput Octet System: Octet® RH16

Ideal for high-throughput applications that demand high sensitivity and low sample volume requirements

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96-Channel Ultra High Throughput Octet System: Octet® RH96

Monitors up to 96 biosensors simultaneously, enabling label-free detection for protein quantitation and kinetic characterization at unmatched speed

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Pioneer FE SPR System

Pioneer FE SPR System

Make Decisions Earlier in Fragment Screens with the Pioneer FE

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