Research the Industry Standard for Label-Free of Biomolecular Interactions Analysis (BIA)

The Octet® BLI platform enables label-free biomolecular interaction analysis based on Bio-Layer Interferometry (BLI) technology. Download the latest application notes, infographics, ebooks, and more to support your label-free research.

Featured Octet® Resources

Biomolecular Binding Kinetics Assays on the Octet® Platform thumbnail

Biomolecular Binding Kinetics Assays on the Octet® Platform

Introducing label-free platforms, the technology, capabilities, and advantages of label-free binding assessment in therapeutics development and life s...

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MAb Quantitation Protein A HPLC vs Protein A Bio-Layer Interferometry

Rapid, accurate and cost-effective quantitation of monoclonal antibodies (MAbs) is essential for bioprocessing.

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Octet R Series System brochure cover

Brochure: Octet® R Series Systems

Accelerate your research with an upgradeable, label-free protein analysis platform

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Cell Line Development: Accelerating Antibody Discovery by Monitoring Titer and Glycosylation With the Octet® Platform

Application Guide: Cell Line Development

Accelerating Antibody Discovery by Monitoring Titer and Glycosylation With the Octet® Platform

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application guide cover

Determining Nanoparticle Vaccine Antigenic Efficiency

Nanoparticle (NP) vaccine and antigen delivery platforms have emerged as a promising approach due to their ability to interact with immune components...

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Octet Formulations and Aggregations app guide cover

Stability, Formulations and Aggregation Studies

Expanding Octet Applications in Downstream Biologics Characterization

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Accurate Measurements on the Octet Platform

Without Added Sample Purification Steps

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Advancing Development of Coronavirus Vaccine and Therapeutics cover

Advancing Development of Coronavirus Vaccine and Therapeutics

BLI Technology Plays a Vital Role in the Race for a SARS-CoV-2 Treatment

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Octet® Kinetics Assay Method Development Guideline

Aimed at developing kinetics binding assays to establish specificity, accuracy, precision, linearity and range as stipulated by the USP 1032 requireme...

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Recent Insights into Covid-19 Binding Epitopes

Bio-Layer Interferometry (BLI) technology is helping scientists around the world learn more about the recent Coronavirus (COVID-19) outbreak. In this...

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Application Note

Rapid, automated, at-line AAV2 virus quantitation advances bioprocessi...

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Octet® Systems in Ligand Binding Assays That Meet Compliance

Octet® systems enable analytical assessment of biologics in various stages of the development workflow beginning with discovery and early selection to...

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Octet® R Series Glycan shadow visual

Mannose Glycans Content Screening for Human-mAb Samples

A novel approach for relative mannose content screening and ranking of human monoclonal antibody (mAb) samples using the Octet® GlyM Kit

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Biomolecular Binding Kinetics Assays on the Octet® Platform thumbnail

Biomolecular Binding Kinetics Assays on the Octet® Platform

Introducing label-free platforms, the technology, capabilities, and advantages of label-free binding assessment in therapeutics development and life s...

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Validated Quantitation and Activity Assay of Antibody Fragment Molecule (Fab) for Process Development and Quality Control

Validated Quantitation and Activity Assay of Fab Molecule for Process...

The group was able to develop a working Fab activity assay on the Octet RED system in less than a week. Relative to the overnight incubation and four-...

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Cover: Characterizing Membrane Protein Interactions by Bio-Layer Interferometry

Characterizing Membrane Protein Interactions by Bio-Layer Interferomet...

Example studies on how the Octet® system can be used to analyze membrane protein interactions, even allowing the use of unpurified crude matrices and...

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Octet® Systems: Modernize Biopharmaceutical QC Testing to Increase Efficiency

Modernize Biopharmaceutical Quality Control Testing

Quality control of biological products to support clinical trials and post market assay activities require the evaluation of multiple critical product...

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Label-Free Technologies for Accurate Determination of Affinity and Kin...

From target molecule identification to lead selection and optimization, equilibrium affinity and kinetics rate constants are critical parameters in th...

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MAb Quantitation Protein A HPLC vs Protein A Bio-Layer Interferometry

Rapid, accurate and cost-effective quantitation of monoclonal antibodies (MAbs) is essential for bioprocessing.

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Octet Potency Assay Development Qualification and Validation Strategie...

A method for evaluating the binding of an Fc gamma receptor III (FcγR) molecule to the widely characterized NIST mAb.

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A Rapid Method to Quantitatively Screen Bispecific Antibodies Using Protein A and Octet® His1K Biosensors

Screen Bispecific Antibody Using Protein A and His1K Biosensors

Rapid quantitative screening of bispecific antibodies using Protein A and HIS1K biosensors

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Octet R Series System brochure cover

Brochure: Octet® R Series Systems

Accelerate your research with an upgradeable, label-free protein analysis platform

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eBook: How Are Label-Free Technologies Used in Early Drug Discovery?

How Are Label-Free Technologies Used in Early Drug Discovery?

Modern analytical techniques designed for real-time analysis and high-throughput capabilities significantly reduce the time to the discovery

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Label-Free Detection Technologies: Key Considerations and Applications cover

Label-Free Detection Technologies: Key Considerations and Applications

Binding interactions in biological samples are dynamic and driven by changes to the environment. The techniques used to characterize these interaction...

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AAV Capsid Titer Data 80% Faster Compared to ELISA

Bioprocess Five Additional Batches of AAV Samples Annually

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Infographic

Infographic: Understanding Covid-19 Vaccine and Therapeutic Developmen...

Learn more about how Octet systems are used to advance Coronavirus research and vaccine development

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Influenza Vaccine Titre Determination Bio-Layer Interferometry (BLI)

Fast, accurate determination of vaccine titre during influenza vaccine manufacture is important in understanding process performance and correctly sca...

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Octet® Bio-Layer Interferometry (BLI) Technology

Label-free alternative for characterizing protein-protein and drug-protein interactions in standard microtiter plate format

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High productivity and process economy in GxP applications with Octet

Quantitation assays must show precision, accuracy, linearity, and reproducibility. To be used for GMP applications, they must be developed with techno...

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Octet® BLI Systems – Unmatched Versatility for Discovery, Development...

Traditional methods for analyzing kinetics of biomolecular interactions such as enzyme-linked immunosorbent assay (ELISA) are often cumbersome and may...

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Rapid Characterization and Selection of SARS-CoV-2 Vaccine Candidates...

Using BLI, we developed a set of assays to identify antibodies with SARS-CoV-2 reactivity, and to enable rapid characterization of SARS-CoV-2 vaccine...

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Bio-Layer Interferometry as a Strategic Platform to Validate Covalent...

This seminar focuses on the unique suitability and application of BLI for the characterization of CIR function at the molecular level.

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Novel High-Throughput Glycoanalytics for Biopharmaceuticals

Improve the overall drug discovery process to increase the success rate of preclinical candidates.

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Integrating Octet® BLI into Early Antibody Discovery Workflows

Improve the overall drug discovery process to increase the success rate of preclinical candidates

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Utilizing Octet Platform for Characterizing Critical Reagents in Suppo...

Understand how Octet® BLI technology for affinity characterization antibodies can benefit critical reagent workflows, such as guiding decision-making...

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Fragment Based Drug Discovery of Co-Factor Inhibitors for p97

Learn how to select potential candidates, the use of Bio-Layer Interferometry (BLI) for fragment screenings, developing label-free assays for small mo...

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In-Depth Presentation On Optimers™️ And Discover The Brand New Octet®️...

discover the new versatile Octet®️ R series and the use of Optimer™️ binders to improve affinity purification of novel biologics

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Octet R Series lab tech

Accelerating Drug Discovery with High-throughput Biomolecular Interact...

Learn how Octet® BLI works in therapeutic discovery and development, including common challenges and solutions.

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Investigating Synthetic Immune Recruitment by Proximity Inducing Molecules - White Paper

Investigating Synthetic Immune Recruitment by Proximity Inducing Molec...

In this white paper, we describe the development of Octet® Bio-Layer Interferometry (BLI) assays that validate and characterize bi-functional small mo...

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Streamlining Affinity Analysis for Accelerated Lead Screening

Antibody and other protein therapeutics are a major focus in drug discovery pipelines today. The overall process for developing protein therapeutics e...

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Writing Grant Proposals for Biomolecular Interactions Research

Grant writing can be a grind. You know how and why the funding is needed, but communicating that successfully sometimes seems like an art. Download ou...

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Enhanced Efficiency in Lot Release and In-Process Testing of Biologics cover

Enhanced Efficiency in Lot Release and In-Process Testing of Biologics

Bio-Layer Interferometry (BLI) is an optical technique that analyzes the interference pattern of white light reflected from two surfaces: a layer of i...

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Biologics Characterization Tools

Industry Standards for Label-Free Analysis of Biomolecular Interactions

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