Octet Label-Free Detection Systems

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Octet BLI Label-Free Detection Systems for Biomolecular Interactions Analysis

Unprecedented Time and Cost Savings For Affinity, Kinetics, and Concentration Assays

Octet systems enable real-time, label-free analysis for determination of affinity, kinetics, and antibody/protein quantitation. Based on Bio-Layer Interferometry (BLI), this fluidics-free instrument platform offers a number of advantages over traditional label-free techniques like Surface Plasmon Resonance (SPR).

  • Higher Throughput - Protein quantitation can be complete in as little as two minutes, and up to 96 samples can be processed simultaneously on the Octet HTX system. 
  • Wider Sample Compatibility - Analytes can be measured in unpurified mixtures such as cell lysates or hybridoma supernatants.  Octet systems tolerate glycerol and even up to 10% DMSO.
  • Lower Total Cost of Ownership - No fluidics modules to clog or cause downtime while waiting for replacements.

Discover Biolayer Interferometry (BLI) Technology

Label-Free BLI Detection Systems

Octet HTX

96-Channel Ultra High Throughput Octet System: Octet HTX

Monitors up to 96 biosensors simultaneously, enabling label-free detection for protein quantitation and kinetic characterization at unmatched speed

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Octet RED384

16-Channel High Throughput Octet System: Octet RED384

The Octet RED384 16-channel instrument provides analytical performance similar to the 8- channel Octet RED96 system, but with higher levels of...

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Octet RED96e

8-Channel Octet System: Octet RED96e

The 8-channel Octet systems perform quantitation of 96 samples in 32 minutes and kinetic screening of 64 samples in 1.5 hours.

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Octet QKe

8-Channel Octet System: Octet QKe

Unmatched versatility for discovery, development, and quality control

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Octet K2

2-Channel Entry-Level Octet System: Octet K2

High performance, research-friendly kinetics characterization

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BLItz System

Personal assay BLItz System

Label-free assays in a drop

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Sartorius Solutions for Label-Free Detection Systems

Analyze samples in crude matrix

Use the fluidics-free Octet systems with 96- and/or 384-well sample plates and the ready-to-use biosensors for flexibility in sample types; from large biologics to small molecules, purified or in crude form.

Transfer methods to QC and manufacturing with confidence

Rapidly develop and validate Octet methods for lot release ligand binding, quantitation, and impurity assays.

Featured Resources

Label-Free Detection Technologies: Key Considerations and Applications

Binding interactions in biological samples are dynamic and driven by changes to the environment. The techniques used to characterize these...

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Enhanced Efficiency in Lot Release and In-Process Testing of Biologics

Bio-Layer Interferometry (BLI) is an optical technique that analyzes the interference pattern of white light reflected from two surfaces: a layer...

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MAb Quantitation Protein A HPLC vs Protein A Bio-Layer Interferometry

Rapid, accurate and cost-effective quantitation of monoclonal antibodies (MAbs) is essential for bioprocessing.

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Octet Potency Assay Development Qualification and Validation...

Real-time data on affinity and the kinetics of binding can provide useful information at every stage of biopharmaceutical reagent development.

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