Tuflux® Tubing for Safe Liquid Transfer
Liquid transfer is an essential part of biomanufacturing processes. With Tuflux® tubing, benefit from low extractable profiles for both silicone and TPE tubing to transfer critical fluids across all process steps.
A Broad Range of Tubing Standards
Tuflux® tubes are available in standard dimensions from 1/8" (3.2 mm) to 1" (25.4 mm) for the internal dimensions and a wall thickness from 1.6 mm to 4.8 mm. These tubes’ function both as non-sterile standalone coils to build your own assemblies and as part of pre-sterilized single-use systems from Sartorius, which include bags, transfer sets, filters, or bioreactors.
There are three types of Tuflux® tubes, the table below will help you assess which one is best suited for your process need:
Attributes | Tuflux® SIL | Tuflux® TPE | Tuflux® SIL Braided |
---|---|---|---|
Sealable | weldable | No | Yes | No |
Recommended for pumping | Yes | Yes* | No |
Recommended for high pressure | No | No | Yes |
Standard dimensions available from stock (IDxOD) | 1/8" x 1/4" (3.2 x 6.4 mm) | 1/8" x 0.355" | |
Extractable guide | validation guide | Yes | Yes | Yes | Yes | Yes | Yes |
Dimensional color coding | No | Yes (YL, OR, RD, WH, GY, BL, BK) | No |
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*for light pumping applications
Process Ready Pumping Performance
Tuflux® SIL Silicone Tubing
Tuflux® SIL is designed to facilitate fluid transfer in biopharmaceutical manufacturing processes. Tuflux® SIL is a highly resistant platinum-cured silicone tubing manufactured by Raumedic.
- Low extractable profile
- Resistant to pumping
- Easy handling
Purity and Cleanliness
Benefit from a silicone tubing with a low extractable profile for the transfer of critical fluids. Sartorius’ platinum-cured silicone tubing undergoes an extensive post-curing process after extrusion to create a product with extremely low levels of siloxanes, the most relevant extractable group within silicone products. Tuflux® SIL tubing is manufactured in ISO 7 cleanrooms to maintain the cleanliness of the drug substances it carries.
Robust Tubing
Tuflux® SIL tubing's hardness of 60 Shore A combined with an optimized wall thickness dedicated per size ensures a solid compromise between pressure resistance and long pump life with high flow rates. Tuflux® SIL has been designed to prevent kinking but maintain enough flexibility for efficient operator handling.
Proprietary Low Tack Treatment
Tuflux® SIL undergoes a surface treatment in a plasma process that reduces the stickiness of the surface when compared to non-surface treated silicone tubing products. This eases the unwinding of coils, as well as handling in general.
More Than Just Another TPE Tubing
Tuflux® TPE Thermoplastic Elastomer Tubing
Tuflux® TPE has been designed specifically for liquid transfer in the biopharmaceutical industry. It can be heat sealed and welded with Biosealer® TC and Biowelder® TC to maintain sterile conditions.
- Ease of use/Error proofing
- Cell-growth compatibility
- High flexibility for use with other materials
Mitigate Errors with Embedded Colors
The unique color-coding of Tuflux® TPE tubing aligns with the Biowelder® TC tube holders. In addition, the printing of the inner and outer diameter dimensions, as well as the tube material, facilitates identification and ease of use and mitigates operator errors.
Tubing Optimized for Cell Growth
Tuflux® TPE has been specifically designed to be compatible with cell growth. Indeed, its antioxidant levels have been optimized in order to prevent any risk of toxicity caused by the presence of bis(2,4-di-tert-butylphenlyl) phosphate (bDtBPP). As a result, cell growth is not inhibited even under worst-case surface-to-volume ratios in small-scale applications.
Co-welding With Other TPE Tubing
Co-welding between Tuflux® TPE and different TPE tubes is possible thanks to Biowelder® TC. Indeed co-welding parameters have been validated for different combinations of gamma-irradiated and/or autoclaved tubes.
High Pressure Resistance Tubing
Tuflux® SIL Braided
Braided Tuflux® SIL is the newest product in the Sartorius tubing portfolio. Its composition is identical to Tuflux® SIL just with an integrated mesh.
- High pressure resistance
- Medical grade PET mesh
- Full validation package for easy adoption
Pressure Resistance
Braided Tuflux® SIL is made of the same silicone as Tuflux® SIL and therefore benefits from the same advantages: low extractable profiles, a good compromise between strength and flexibility and a low tack treatment to reduce surface stickiness. It is reinforced with a mesh, enabling it to be resistant to pressures up to 60 bar.
Medical Grade Mesh
Braided Tuflux® SIL is reinforced with a medical grade PET mesh material which enables high pressure resistance while ensuring that your fluids are kept safe.
Braided Tuflux® SIL is available in 6 different dimensions to fit your process requirements. It can be ordered non-sterile as stand-alone coils or assembled on our single-use products. If you already use Tuflux® SIL, there is no extra validation work needed. Otherwise our validation and extractable guides will ease integration of Tuflux® silicone products in your processes.
Related Products
Biowelder® Total Containment (TC) and Biosealer® TC provide innovative solutions to complement your Tuflux® TPE system.
Learn More About Tuflux® Tubing
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Related Topics
Tubing assemblies from Sartorius enable flexibility in all process steps. Select a predesigned single-use tubing set or configure a custom design from an extensive component library.