Biosealer® TC Aseptic Tube Sealing Device
Automated Aseptic Thermoplastic Tubing Disconnection
Progressive biomanufacturing processes require advanced tools to reliably disconnect components. The Biosealer® Total Containment (TC) is an automated heat sealer for disconnecting thermoplastic tubing in an aseptic operation maintaining sterile fluid paths. The Biosealer® TC handles disconnections between disposable assemblies used in biopharmaceutical manufacturing processes and individual components of assemblies, even in non-sterile environments, while maintaining the product’s sterility.
- Use tube sizes from 1/4" to 1" OD — no accessory needed
- Dry, wetted or liquid-filled tubes
Preset for sealing up to 6 sizes of the industry’s 5 most-used TPE tubing types*
- Goes with operator to disconnection site
- Use in tabletop or hanging mode
- 20 mm wide seal for robust disconnection
- Operator uses embedded cutting guide for scissor snip
Discover the Simplicity of the Biosealer® TC
The Biosealer® TC simplifies heat-sealing with a user-friendly portable design, highly stable thermal seals and a new level of flexibility. See the video to learn how the Biosealer® TC enhances thermoplastic tube-sealing.
Market-Leading Sealing Performance
Versatile Automated Sealing Device
The Biosealer® TC automated sealing device provides a simple, flexible, and fast solution for making sterile disconnections across all biopharmaceutical manufacturing processes. It can be used on disposable bags, unit operations and single-use tubing assemblies and can seal wet, dry or liquid-filled tubing.
|Biosealer® TC Aseptic Sealing Device|
Intuitive user interface
|Selecting the tubing material and size to be sealed is very easy using Biosealer® TC touch screen. Operators are then guided in a step-by-step process displayed on the screen.|
Variety of qualified materials
Compatible with Tuflux® TPE, C-Flex® 374, AdvantaFlex®, Sanipure™ BDF™ and PharMed® BPT.
Variety of tube sizes and conditions
Has 1/8" × 1/4" up to 3/4" × 1" (ID × OD) capability, including liquid-filled conditions, no accessory needed.
The Biosealer® TC is lightweight and can be operated on a table or while hanging. Plus, the Biosealer® TC is portable and can be moved to where the sterile disconnection is desired.
The Biosealer® TC offers a wide 20 mm seal for more robust disconnection. In addition, a cutting guideline embedded into the seal ensures operators can make a clean cut with scissors.
Four Easy Steps to a Strong Seal
Insert TPE Tubing
Insert the TPE tubing in the device where the sterile disconnection is desired.
One click on the touch screen is sufficient to start the sealing process. Just follow the instructions displayed.
Remove TPE Tubing
When the sealing process is complete, the lid automatically reopens.
Cut the Sealed TPE Tubing
After visual inspection of the sealing, use scissors to cut through the guideline on the sealed tubing. Done!
Biosealer® TC Applications
Disconnect With Flexibility
Biosealer® TC can seal wet, dry or liquid-filled tubing in non-classified and classified environments while maintaining product sterility.
Disconnect at Every Step
From small-scale upstream processes to final filling applications in large commercial productions, the Biosealer® TC adapts to changing disconnection needs.
Disconnect Across Applications
Create sterile seals for cell line development, cell and gene therapeutics and the production of mAbs, vaccines, and biosimilars.
Take a Closer Look
Biosealer® TC Components, Accessories and Services
Maximize sealing ability and smooth operations with useful accessories. Regular Sartorius service maintains peak performance.
Biosealer® TC System
The Biosealer® TC is a robust, flexible and easy-to-use device that generates sterile TPE tubing disconnections.
Ensure top Biosealer® performance with a temperature calibration kit.
Enhance the device’s portability with a 3 m extension cable.
Regular maintenance by Sartorius service engineers ensures top performance. Qualified services are available for GMP environments.
Sartorius Provides Complete Tube Sealing and Welding Solutions.
Consult Our Experts
*Including Tuflux® TPE, C-Flex® 374, AdvantaFlex®, SaniPure™ BDF ™ and PharMed® BPT . C-Flex®, SaniPure™ and PharMed® are registered trademarks of Saint-Gobain Performance Plastics Corporation. AdvantaFlex® is registered trademark of AdvantaPure.