Tangential Flow Filtration Systems

TFF Systems: Process Solutions for Ultrafiltration and Diafiltration

Sartorius offers flexible tangential flow filtration (TFF) systems spanning the molecule discovery phase through to commercial production. Covering process development and clinical trials, our portfolio of TFF skids can meet virtually any requirement. Production processes can be optimized effectively using the wide range of cost-efficient crossflow systems that include multi-use setups as well as equipment with single-use flow kits, allowing for aseptic processing.

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TFF Systems Portfolio

Find the Right TFF System

Enhance your operations with Sartorius' versatile filtration solutions, designed to simplify workflows and boost efficiency, enabling seamless integration into your bioprocessing activities.

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Ambr® Crossflow TFF System: Parallel Screening and Optimization

Compatible with hollow fiber and flat sheet consumables, the adapter kit supports four consumables simultaneously.

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Sartoflow® Smart: A Modular, Small-Scale TFF System

The crossflow system built for process development: Achieve high product yields with a low-shear membrane pump.

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Sartoflow® Advanced: A Modular Benchtop TFF System

Flexible TFF from process development and clinical trials to small-batch cGMP production.

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Sartoflow® Expert SU: Versatile Single-Use TFF

Combine three ADC unit operations in a single automated, single-use TFF system—from process development to pilot-scale manufacturing.

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Sartoflow® 1000: Pilot-Scale Single-Use TFF

Fully automated ultrafiltration and diafiltration processes for batch volumes of 20 to 200 L.

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Sartoflow® 4500:  Commercial-Scale Single-Use TFF

Fully automated ultrafiltration and diafiltration processes for batch volumes of 200 to 2,000 L.

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Supporting Products & Services

Browse TFF Cassettes for Every Application

Find your TFF solution with our cutting-edge options, tailored to your unique needs. Boost operations with precision and innovation.

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Robust TFF Holders

Sartocon® and Sartoflow® TFF holders offer advanced flexibility, ensuring predictable performance from process development to production.

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Achieve Gentle Processing With Hollow Fiber Filters

Engineered for gentle handling of sensitive products, hollow fiber filters ensure efficiency, care, and optimal performance with every use.

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Brochure

Tangential Flow Filtration Portfolio

Find the optimal combination of cassettes and systems for your filtration needs, ensuring high recovery rates and optimal flow rates.

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Related Assets

Case Study

Enhancing Efficiency: Piramal's Innovative Approach

Piramal achieved a 70% shorter timeline with easy single-use setup, retaining high performance using Sartoflow® Expert.

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Tutorial

Sartoflow® Expert SU Demo Video

Showcasing Sartoflow® Expert SU: A versatile single-use TFF system designed for efficiency and safety.

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Webinar

From 10 Days to 3: Transforming ADC Processes With Single-Use Tools

Watch our webinar to see the impact of single-use TFF systems on process efficiency at Piramal Pharma Solutions

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Application Note

Unveiling Advanced TFF Methods for Adenovirus Purification

Learn how Sartoflow® Smart enhances adenovirus purification with innovative ultrafiltration and diafiltration methods.

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Application Note

Seamless Integration of Hollow Fiber Modules with Sartoflow® Systems

Discover the seamless integration of Sartorius' hollow fiber modules with Sartoflow® 1000 & 4500, enhancing filtration performance.

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Webinar

Optimize Your GLP-1 Agonist Purification

Watch our webinar to discover strategies for mastering GLP-1 agonist production, along with proven, robust technologies tailored for peptides.

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Related Services

Explore Services for Your Research and Biomanufacturing Equipment

Discover how Sartorius services help maintain and extend the lifespan of your research and biomanufacturing equipment while minimizing downtime.

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