TFF Systems: Process Solutions for Ultrafiltration and Diafiltration
Sartorius offers flexible tangential flow filtration (TFF) systems spanning the molecule discovery phase through to commercial production. Covering process development and clinical trials, our portfolio of TFF skids can meet virtually any requirement. Production processes can be optimized effectively using the wide range of cost-efficient crossflow systems that include multi-use setups as well as equipment with single-use flow kits, allowing for aseptic processing.
TFF Systems Portfolio
Find the Right TFF System
Enhance your operations with Sartorius' versatile filtration solutions, designed to simplify workflows and boost efficiency, enabling seamless integration into your bioprocessing activities.
| Attributes | Ambr® Crossflow | Sartoflow® Smart | Sartoflow® Advanced |
|---|---|---|---|
| Membrane Area | 10, 50 cm² | 50 cm² - 0.14 m² | 0.1 – 0.21 m² |
| Vessel Volume | 100 mL | 1 L with mixing | 10 L |
| Flow Rate / Pump Capacity | 0 – 80 mL/min | 1 – 100 L/h | 700 L/h |
| Minimum Recirculation Volume | 5 mL | < 20 mL | ~ 170 mL |
| Automation Level | Fully | Semi | Fully |
| Process Mode (multi/single) | Multi-use or single-use | Multi-use | Multi-use |
| Learn More | Learn More | Learn More |
| Attributes | Sartoflow® Expert SU | Sartoflow® 1000 | Sartoflow® 4500 |
|---|---|---|---|
| Membrane Area | Flat sheet: 0.1 – 0.4, 1.4 m² | Flat sheet: 0.6 - 2.8 m² Hollow fiber: 0.13 - 2.5 m² | Flat sheet: up to 10 m² Hollow fiber: 2.69, 5 m² |
| Vessel Volume | 20 L mixing | 10, 20, 100 L | |
| Flow Rate | Pump Capacity | 900 L/h | 20 – 900 L/h | 100 – 4500 L/h |
| Minimum Recirculation Volume | ~ 600 mL | ~ 1.2 L | Depends on bag size |
| Automation Level | Fully | Fully | Fully |
| Process Mode (multi | single) | Single-use | Single-use | Single-use |
| Learn More | Learn More | Learn More |
