Sartoflow® Advanced - The Modular Benchtop TFF System
Full Flexibility Meets Outstanding Performance
The Sartoflow® Advanced is a modular benchtop tangential flow filtration (TFF) system optimized for ultrafiltration and diafiltration (UF | DF) applications used in many downstream processes, such as the purification of vaccines, monoclonal antibodies, and recombinant proteins. The system is suitable for flexible use in laboratory environments for process development as well as clinical trials and small batch cGMP production.
- Membrane surface areas from 0.1 m² to 2.1 m²
- Stainless-steel recirculation vessel or single-use bags
- Easy-to-use out of the box with predefined sequences
- 4-piston membrane pump for low shear
- Two pumps for feed and buffer addition, as well as full TMP control
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Sartoflow® Advanced Overview

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Frequently Asked Questions
The Sartoflow® Advanced is ideal for ultrafiltration, microfiltration, and diafiltration, especially in purifying vaccines, monoclonal antibodies, and recombinant proteins in labs, clinical trials, and small-scale production under cGMP conditions.
Yes, modular options are offered for customization and upgrades, allowing adaptation to specific application needs.
The Sartoflow® Advanced System uses Biobrain® Supervise software for data collection and monitoring, with logs stored for analysis via optional SCADA software.
Options include a stainless-steel tank or single-use bags, both designed to prevent foaming and ensure efficient recirculation.