Sartoflow® Advanced TFF System

Sartoflow® Advanced - The Modular Benchtop TFF System

Full Flexibility Meets Outstanding Performance

The Sartoflow® Advanced is a modular benchtop tangential flow filtration (TFF) system optimized for ultrafiltration and diafiltration (UF | DF) applications used in many downstream processes, such as the purification of vaccines, monoclonal antibodies, and recombinant proteins. The system is suitable for flexible use in laboratory environments for process development as well as clinical trials and small batch cGMP production.

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Flexible Solution for UF | DF
  • Membrane surface areas from 0.1 m² to 2.1 m²
  • Stainless-steel recirculation vessel or single-use bags
Intuitive and User-Friendly
  • Easy-to-use out of the box with predefined sequences
High Product Yields
  • 4-piston membrane pump for low shear
Highly Automated
  • Two pumps for feed and buffer addition, as well as full TMP control

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Sartoflow® Advanced Overview

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Performance Deep Dive

Match the System to Your Needs

The Sartoflow® Advanced is a modular benchtop TFF (crossflow) system with many options:

  • Ideal for both process development and small-scale production

  • Can accept either Sartocon® Slice or full-sized Sartocon® cassettes for a wide range of membrane surface areas

  • Stainless-steel recirculation tank or single-use bags

  • Touch screen control interface

  • Full compatibility to BioPAT® MFCS software

Intuitive, User-Friendly Controls

  • All control and alarm functions accessed via the 12" touch screen

  • Operators have immediate process control

  • Option to use predefined parameters to automatically run customized sequences for concentration, UF | DF, rinsing, filling, draining, and flushing steps

  • Feed pressure and level controllers are standard

  • BioPAT® MFCS software is standard

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Frequently Asked Questions

The Sartoflow® Advanced is ideal for ultrafiltration, microfiltration, and diafiltration, especially in purifying vaccines, monoclonal antibodies, and recombinant proteins in labs, clinical trials, and small-scale production under cGMP conditions.

Yes, modular options are offered for customization and upgrades, allowing adaptation to specific application needs.

The Sartoflow® Advanced System uses Biobrain® Supervise software for data collection and monitoring, with logs stored for analysis via optional SCADA software.

Options include a stainless-steel tank or single-use bags, both designed to prevent foaming and ensure efficient recirculation.

Supporting Products & Services

Sartocon® and Sartocube® Microfiltration Cassettes

Evaluate high-performance microfiltration solutions tailored to your specific process needs.

Sartocon® and Sartocube® Ultrafiltration Cassettes

Explore cutting-edge concentration and diafiltration solutions to fit your individual process needs.

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