Mycap® Aseptic Bottle Closures
Advancing the Function, Handling and Performance of Plastic and Glass Containers
Do more with centrifuge tubes, bottles, flasks and carboys fitted with a Mycap® closure. Mycap® improves container functionality by integrating tubing with the cap, which provides practical and dependable aseptic fluid handling. The versatile platform makes it possible to adjust the number, size and material of tubes in the cap without compromising the Mycap® high-performance platinum-cured silicone seal, allowing you to configure a system that fits your process applications.
Plasticizer-free, platinum-cured silicone seal maintains closure integrity and retains its physical properties from -65°C to > 200° C.
From the inventive dip tube tip for maximum fluid removal to the QUICKSEAL® aseptic disconnection, Mycap® is an adaptable solution for any application.
Mycap® is built with the same, proven closure system regardless of the container or tubing materials. Validate Mycap® once, and use it freely across the entire production process.
The Making of Mycap®
Learn more about our unique approach to manufacturing and how this unlocks the configurability of Mycap®.
A Comprehensive Family of Mycap® Bottle Closures*
Sartorius regularly adds new offerings to its Mycap® portfolio, but also provides solutions for the most popular containers and cap sizes.
Contact us for the most up-to-date list of qualified bottle caps.
Cap Size/Style | Common Containers | Examples | Offered As |
---|---|---|---|
GL25 | Glass Laboratory Bottles | Duran®, Pyrex® | Standalone for field installation |
20-415 | Single-Use Plastic Bottles and Centrifuge Tubes | Nalgene®, Falcon®, Greiner Bio-One | Assembled system inclusive of bottle(s) |
53B | Single-Use Plastic Bottles and Carboys | Nalgene® | Assembled system inclusive of bottle(s) or Standalone for field installation |
33 mm | Single-Use Centrifuge Tubes | Falcon®, Greiner Bio-One | Assembled system inclusive of bottle(s) |
33 / 38 / 48 mm | Plastic Erlenmeyer Flasks and Single-Use Centrifuge Tubes | Falcon®, Greiner Bio-One | Assembled system inclusive of bottle(s) |
What Makes Mycap® Special?
High-Performance Closure
Mycap® silicone closure is plasticizer-free, stabilizer-free and has no antioxidants. The low stress-to-seal design provides a highly compliant and reliable closure with outstanding compression set and low creep properties.
Mycap® is an ideal closure for most biopharmaceutical applications.
Protect from Product Loss
Purpose-built dip tube tip prevents suction during fluid removal. The subtle saddle shape ensures fluid removal down to the very last drop.
Direction Where You Need It
The Z-Flex Articulator is an elegantly simple design that is remarkably effective at keeping fluid inlet lines where they are needed or dip tubes away from other accessories in the bottle.
Intuitive and Simple Aseptic Disconnection
Quickseal® delivers simple and fast aseptic disconnection. Cut the collar to disconnect a filled bottle and seal the tubing in one simple step. Mycap® closures combined with Quickseal® disconnection provide a reliable system for critical fluid-management processes.
Secure Manifolds
Stopcock valve assemblies are compact, have integral valves for precise directional fluid flow control and reduce the number of connection points. The manifolds have Luer fittings and a Luer lock accessory to resist unscrewing, bringing a new level of security to stopcock valve assemblies.

Making the Most of Mycap®
Selected Applications
Mycap® assemblies are well-suited for most biopharma, vaccine or cell and gene therapy applications where closed, aseptic fluid handling is required. Explore below to learn more about the targeted applications for Mycap® single-use assemblies.
Aseptic Sampling
Small bottles and centrifuge tubes are ideal for sample collection, and the integral tubing and secure silicone seal of Mycap® prevent contaminations and false positives.
Media and Buffer Preparation
Bottles with Mycap® closures, either singles or manifolds, are the preferred containers for collecting and storing media or buffer. The dip tube tip gets the last drop of media out.
Bioreactor Feeds
Tubing of a Mycap® closure with dip tube can be aseptically welded or connected to tubing from a bioreactor, providing an aseptically closed feed system to transfer acid, base and other supplements.
Small Volume Mixing System
Add a Mycap® closure to bottles and flasks equipped with a magnetic stir bar to benefit from aseptic fluid-handling in your small-scale mixing system. Both standalone and fully assembled Mycap® solutions are available.
Drug Product Freeze and Thaw
Add Mycap® to bottles and carboys used for freeze/thaw operations to dramatically improve filling and draining by making each an aseptically closed system and liberating the process from the confines of biosafety cabinet.