Secure Your Competitive Edge With Process Intensification

The pace of innovation in the biopharmaceutical industry is accelerating rapidly, and manufacturers need to reduce drug costs and increase productivity to stay competitive.

Secure your competitive edge with process intensification and set the foundation for future innovation by optimizing every step of your workflow. It’s never been more important to intensify — and with expert-to-expert insight, cutting-edge solutions, and maximized operational value, it’s never been easier.

It’s time to intensify.

Cut your footprint by more than

50%

icon-reduce-footprint

Shorten timelines by up to

80%

icon-shorten-timelines

Reduce Cost of Goods below

$50/g

icon-lower-cost-of-goods

Expert Guidance

Turn Complexity Into Clarity and Obstacles Into Outcomes

Easily navigate process intensification at any stage with expert insight and support based on demonstrated results.

Get your implementation strategy right the first time by using our expert tools and free stepwise consultancy services to predict cost, processing times, and productivity gains for your entire biomanufacturing process. Leverage state-of-the-art technologies designed to meet future needs using insights gleaned from our industry-leading partnerships. Once implemented, keep your process up-and-running with access to trusted support from our global network of field application specialists.

Discover how Sartorius can transform your biomanufacturing process

Whether you're designing a new facility or optimizing an existing one, our services span the entire manufacturing lifecycle from early development to full-scale commercial production.
 

 icon-plan

Your Vision, Our Expertise

Whether you’re building a facility from scratch or enhancing an existing workflow, we can help you design and execute a powerful, future-ready intensified biomanufacturing strategy.

Connect with a Sartorius Expert

Cutting-Edge Solutions

Optimize Performance, Meet Demands, and Drive Discovery

Whether your business is facing demands in efficiency, sustainability, or both, process intensification provides the foundation to deliver results and drive innovation.

Achieve up to a ten-fold increase in throughput by intensifying your upstream process with rocking motion, stirred-tank, and perfusion-enabled bioreactors. Cut processing times and costs downstream with membrane and continuous chromatography, virus inactivation, SPTFF, and more. Once intensified, connect your processes to multiply your annual manufacturing capacity two- to three-fold without changing your physical footprint.

icon-flask-and-thermometer

Process Development PI Strategies & Solutions

Design an intensification strategy for process development that’s flexible and scalable.

Explore PD PI Solutions
icon-locations

Commercial Manufacturing PI Strategies & Solutions

Deliver reliable performance at commercial scale with robust, intensified processes.

Explore Commercial PI Solutions

Maximize Operational Value

Unlock Business Growth and Stay Ahead of the Competition

Unlock business growth and stay ahead of the competition by integrating end-to-end solutions that deliver the full potential of process intensification.

With scalable single-use bioreactors, ready-to-use modular downstream systems, and advanced digital solutions that maximize operational value, you can cut your footprint by more than 50%, shorten timelines by up to 80%, and drive cost of goods below $50 per gram of final antibody. Our technologies are backed by our continuous investment in innovation, fueling the competitive edge you need to secure growth today and help more patients tomorrow.

Video Series | Expert Insights on Process Intensification 

Hear leading voices in biomanufacturing explore what it takes to implement intensified processing.

Process Intensification: Challenges, Trends, and Industry Takeaways

“It’s no longer a case of ‘if’ and ‘when,’ the fact is it’s happening now.” Experts unpack the realities of process intensification.

Sartorius and the Future of Biomanufacturing

We are committed to advancing PI technologies through strategic planning, tech innovation, and collaboration with our customers.

How Process Intensification Supports a Sustainable Future

Unlocking sustainability: Listen as our experts discuss the environmental benefits of intensified bioprocessing.

Learn More About Process Intensification

Featured Assets

White Paper

A Comprehensive Look at Intensification Strategies for mAb Processes

​​Don’t miss out on real-world guidance for intensifying your mAb process—upstream, downstream, and analytics—in one practical white paper.​ 

Webinar

Time to Intensify: Taking mAb Manufacturing to the Next Level 

Watch this on-demand webinar to learn practical intensification strategies in use today, including perfusion, continuous downstream, and integrated au...

eBook

Top Considerations for Choosing Process Intensification Strategies

Get expert insights into the multifold benefits of process intensification for biologics manufacturing.

Article

Discover the First Proof-Of-Concept for a Connected Downstream Process

Learn how a fully connected, membrane-based downstream process can purify higher volumes with less membrane and at a lower cost.

Related Assets

White Paper

Time to Intensify: Taking mAb Manufacturing to the Next Level

PDF | 3.0 MB
Poster

Proof of Concept for MAbs Purification: From Batch to Intensified and Connected Process

PDF | 643.9 KB
Success Story

Increased Productivity With Concentrated Fed-Batch

PDF | 319.0 KB
Poster

Simplify Upstream Process Intensification From PD to Manufacturing

PDF | 1.3 MB
Application Note

Intensifying a mAb Polishing Platform — Targeting Time, Cost, and Space Efficiency

PDF | 972.3 KB
Success Story

N-1 Perfusion High Inoculum Fed-Batch for Reduced COGS and Easy Retrofit

PDF | 318.4 KB
Success Story

Improve Productivity and Reduce Risk with Biostat® RM

PDF | 199.6 KB
Application Note

Integrated | Connected Downstream Processing of mAbs With Resolute® BioSC for Improved Productivity, Cost, Footprint, and Facility Utilization

PDF | 524.3 KB
White Paper

Re-Imagining Chromatography - Building Efficient, Connected Downstream Processes

PDF | 2.4 MB
Poster

Scalability of Cost Effective 2D Rocking Motion Bioreactors with Internal Filter Membrane for Perfusion Processes.

PDF | 502.9 KB

Webinars

icon-webcast

Maximizing Productivity Using Process Intensification

Experts from Sanofi, Evotec Biologics, and Sartorius share insights and strategies from their experiences implementing PI technologies.

Watch Webinar
icon-webcast

A Holistic Approach to Process Scale-Up

Learn how you can leverage Sartorius scaling tools and MVDA analysis to attain and validate a seamless scale-up.

Watch Webinar
icon-webcast

How to Optimize Cell Lines to Realize the Promise of PI

Explore how cell insights by Umetrics® studio can streamline the development of early-stage upstream intensified processes

Watch Webinar
icon-webcast

Intensifying mAbs Processing for Robust Manufacturing

Connecting & intensifying your mAbs processing can improve productivity. See an example in action in this ondemand webinar.

Watch Webinar
icon-webcast

What Might Be Missing In Your USP Intensification Plan

Explore Sartorius PAT and data analytics that can be used stand-alone or in combination to develop intensified processes.

Watch Webinar
icon-webcast

See the Unrivaled Modular Seed Train for Process Intensification

Experts present a modular, perfusion-enabled seed train featuring Biostat® RM followed by a seamless seed transfer to a Biostat STR® bioreactor.

Watch Webinar
icon-webcast

The Missing Link in Your PI Plan

Explore the implications of media management in an intensification strategy in this webinar featuring Sartorius experts.

Watch Webinar
Article

A Strategic Approach To Selecting the Optimal Process Intensification Scenario

PDF | 540.0 KB
Article

Enabling Broader Adoption of Process Intensification in Biopharma

PDF | 671.0 KB
Article

Streamlining Purification: Proof of Concept for a Fully Connected Downstream Process

PDF | 1.0 MB
Article

Shaping the Future of Biomanufacturing

PDF | 12.7 MB
Article

Intensified Seed Train Strategy for Faster, Cost-Effective Scale-Up of Biologics Manufacturing

PDF | 717.3 KB
Article

Re-Imagining Chromatography - Navigating the Path to Downstream Intensification

PDF | 567.6 KB

Videos

The Why, How, and When to Implement Process Intensification

Change can be risky, but also beneficial. Watch this video to learn about the benefits of using PI to overcome common challenges in biomanufacturing. Sartorius experts describe how PI components can help organizations implement changes gradually that will contribute to lower COGS, a smaller facility footprint, higher productivity, and faster time to market.

The Changing Landscape of Single-Use Technologies and Process Intensification

The industry is redefining regulatory and industry standards due to the implementation of single-use technologies. How does this affect the benefits of process intensification? Watch Miriam Monge in discussion with Dan Stanton, Editor of Bioprocess Insider.

Why is the Biomanufacturing Industry Moving Towards Process Intensification?

Miriam Monge talks about the significance of intensified and continuous processing, the importance of the arrival of biosimilars on the market, and exciting Sartorius developments in the commercial biomanufacturing industry.

Single-Use and Process Intensification in Commercial Biomanufacturing

How do single-use facilities influence cost of goods, flexibility, and reduced footprint in biopharmaceutical manufacturing and how does process intensification play a role? Watch Gerben Zijlstra in discussion with Dan Stanton, Editor of Bioprocess Insider.

Events

BioTalk EU 2025 | Germany

Explore how process intensification can unlock efficiency and speed across the biopharma lifecycle by joining our talk on Sept 17, 4:45 p.m., at BioTalk EU 2025 in Berlin.

Visit the Event Page

FAQs for Process Intensification

Process intensification in biopharmaceutical manufacturing is a transformative approach aimed at enhancing the efficiency and productivity of bioprocesses. By adopting intensified bioprocessing techniques, manufacturers can achieve significant improvements in continuous biomanufacturing and connected bioprocessing. This strategy focuses on optimizing resource utilization, reducing production time, and increasing output, ultimately leading to more sustainable and cost-effective bioprocess manufacturing. Embracing Bioprocessing 4.0, process intensification integrates advanced technologies to streamline operations and drive innovation in continuous manufacturing for pharmaceuticals.

Intensified bioprocessing offers benefits across organizations, including small biopharma, contract development and manufacturing organizations (CDMOs), and large pharmaceutical companies. These benefits include increased bioprocessing productivity, reduced cost of goods, enhanced flexibility, and rapid scalability. By transitioning to process intensification, companies can maximize operational value, reduce their manufacturing footprint, and achieve sustainable biopharma production.

We support sustainable process intensification by offering innovative bioprocess solutions and consulting services. With a focus on sustainability in biopharma production, we provide process intensification platforms and technologies that enable companies to reduce their manufacturing footprint, increase productivity, and achieve long-term operational value.

Process intensification improves continuous biomanufacturing by streamlining operations, reducing production time, and increasing output. By implementing intensified bioprocessing techniques and connected processing solutions, companies can achieve seamless and efficient continuous manufacturing of pharmaceuticals, leading to enhanced productivity and sustainability.

Bioprocess intensification uses a range of technologies, including automated bioprocess solutions, intensified processing technology, and connected processing platforms. These technologies enable companies to optimize their bioprocesses, increase efficiency, and achieve sustainable production. By leveraging these advanced tools, companies can successfully implement process intensification and enhance their manufacturing capabilities.

Consult Our Experts

Consult Our Experts

Need help?