Intensification of mAb Downstream Processing with Full Membrane Chromatography Workflow 

Wednesday, November 5, 2025

Session 1:   10 a.m. CET | 1:30 p.m. IST | 4 p.m. HKT   

Session 2:  8 a.m. PST |  11 a.m. EST | 5 p.m. CET

 

In protein-based therapies, the demand for efficient and flexible manufacturing processes is increasing due to their potential to reduce costs of goods, enable wider drug accessibility, increase capacity, and reduce process footprint. Manufacturers have started to leverage single-use facilities and advancements in upstream processing to drive process intensification — and while this has increased mAb titers, it’s also amplifying productivity bottlenecks downstream and driving the need for chromatography process intensification.  

This webinar presents a lab-scale study and a scale-up model that can predict the cost and productivity benefits of implementing a full membrane chromatography workflow for mAb purification, from process development to GMP commercial manufacturing. The speakers will demonstrate how membrane chromatography can purify large amounts of antibodies faster, with fewer consumables, and in a smaller facility footprint, all while meeting the product quality attributes.

 

What You Will Learn:

  1. Explore the benefits of process intensification (PI) and how to ensure successful implementation
  2. Anticipate PI challenges and solutions when transitioning to intensified processes
  3. Discover cost-modeling tools for implementing a full membrane chromatography process

 

 

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Meet Our Experts

Jean-Marc Cappia

Head of Market Development Intensified Chromatography

J.M. Cappia is Head of Market Development, Intensified Chromatography, at Sartorius, based in Aubagne, France. A Biotechnology Engineer graduate from INSA Toulouse with more than 35 years of experience, Mr. Cappia supports the biopharmaceutical industry globally, particularly in process design, process intensification, validation, training, and implementation of single-use filtration, purification, and fluid management technologies.  

Since joining Sartorius in 2006, he has been responsible for marketing, product management, and business development for emerging single-use technologies. In his current position, he supports the biopharmaceutical industry in implementing downstream process intensification, focusing on chromatography, with the objective of producing safer and more cost-effective biologics in more sustainable manufacturing facilities. 

 

Yitao Feng

Director of BD Technical Support & Purification Process Development

Dr. Feng is Director of Purification Process Development and a project leader for customer projects at BioDlink. In this role, he provides technical leadership in project execution and group management. Dr. Feng holds a PhD from Hong Kong University of Science and Technology.