Aseptic Connections

Connect With Endless Possibilities

Modern single-use biomanufacturing involves many manual connections to maintain a closed fluid path across process steps. Sartorius' proven connection portfolio adds simplicity, flexibility and speed to any operation. These products provide consistent performance, thanks to robust designs coupled with maintenance and operator training services. Stringent validation protocols assure sterility.

Simplicity

Designed with the user in mind, Sartorius’ equipment reflects years of customer feedback and experience.

Flexibility

Sartorius has a diverse portfolio of connection components to meet customer needs.

Speed

Save time with thermal and mechanical connection technologies that streamline steps between drug development and manufacturing.

Connect with Confidence

Aseptic connection technology is critical to successful fluid transfer. Sartorius can aid in planning the connections between unit operations to ensure proper containment. A full line of connection technologies offer simplicity, flexibility and speed to suit process needs, streamline operations and protect valuable process fluids. 

 

 Biowelder® TC Sterile Tube Welder Opta® SFT Aseptic Tube ConnectorsTriclampQuick Couplers
Type of Connection

Sterile

Sterile

Non-sterile

Non-sterile
Maintains sterility in non-classified environmentsYesYesNoNo
Time1-4 mins30 secs1 min< 30 secs
Typical Tubing materialTPE OnlyTPE / Silicone (braided)TPE / Silicone (braided)TPE / Silicone / EVA
Process FlexibilityAs needed with no pre-defined locationPre-designed in single-use assemblyPre-designed in single-use assemblyPre-designed in single-use assembly
Cost per connection$*$$$$$$
Fluid contact materialsNonePCPolypropylene / PEPolycarbonate / Polysulphone
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*Initial CAPEX is required

Biowelder® TC Sterile Tube Welder

Biowelder® Total Containment is a fully automated welder for sterile connection of thermoplastic tubing. This patented technology allows sterile connection of dry- or liquid- filled TPE tubing. The Biowelder® TC thermally welds tubing from 1/4" up to 1" OD for a stable aseptic connection.

Explore Biowelder® TC

Biowelder® S Automated Aseptic Welder 

The Biowelder® S is a fully automated solution for sterile welding of thermoplastic elastomer (TPE) and polyvinyl chloride (PVC) tubing. Designed for GMP manufacturing, and specifically CGT processes, it ensures aseptic connections of tubing, supporting different sizes and materials with a universal tube holder.

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The Opta® Sterile Fluid Transfer (SFT)

Sartorius’ range of aseptic connectors allows fast and reliable connections for sterile fluid transfer between two separate, pre-sterilized process components in biopharmaceutical manufacturing operations. The gendered Opta® connectors determine the direction of process flow and eliminate operator connection errors.

Explore Opta® SFT

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Sartorius Single-Use Connection Solutions

Maintain sterility with easier handling and build speed, flexibility and redundancy into your process with a broad range of tube sizes, material compatibilities, and interconnectivity between different sizes and materials.

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Related Products

Confidence® Validation Services

Confidence® proves the resistance and integrity of the containers under real and/or simulated shipping conditions

Tubing Sets and Assemblies

A comprehensive portfolio of standard and custom tube sets for transfer, distribution or filling of in-process fluids.

Learn More About Aseptic Connections

Success Story

How Large Pharma Used Connection Redundancies and Single-Use Systems to Streamline Production

PDF | 230.1 KB

Consult Our Experts

Consult Our Experts

Related Topics

Confidence® Validation Services

Benefit from more than 25 years of experience. We support you from compatibility to E&L to integrity-related validation requests.

Liquid Storage and Shipping

Flexsafe® 2D and 3D single-use bags are designed to store and transport all bioprocessing fluids.

Mixing

Flexsafe® Single-Use Mixers improve quality and increase efficiency across mixing operations.

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