Sample Preparation for Optimized Workflows
Accurate and reliable experimental results depend on proper sample preparation, which minimizes variability, enhances detection sensitivity, and ensures samples are reproducible and precise—ultimately strengthening the credibility of scientific research.
Sartorius provides reliable and reproducible solutions for every stage of the sample preparation workflow, ensuring accurate and consistent measurements.
From precision weighing and liquid handling to ultrafiltration and sedimentation, our Lab Essentials support researchers in academia, biotechnology, and the pharmaceutical industry.
Whether preparing cell cultures or isolating biomolecules for downstream analysis, Sartorius delivers end-to-end solutions that streamline workflows and enhance research efficiency.
Sample Preparation Applications and Solutions
Cell Culture Setup with Innovative Lab Tools
Reliable and reproducible results start with the right lab tool. Sartorius supports your research with solutions that simplify workflows, enhance efficiency, and minimize the risk of errors or contamination.
From improving accuracy in sample preparation to ensuring consistent water quality and safe liquid handling, our Lab Essentials help you work smarter and with greater confidence—so you can focus on what matters most, generating meaningful scientific results.
Solutions
Rapid harvesting, concentration and purification of biomolecules from cell culture for downstream analytics
Ensure a seamless purification workflow with solutions designed to save time, maximize yield, and maintain the integrity of your target molecules. Sartorius supports every step of your lab-scale purification process—from efficient clarification and concentration to reliable buffer exchange and final sterile filtration.
Our technologies help streamline your workflows, reduce hands-on time, and boost reproducibility, so you can achieve high-quality results with greater speed and confidence.
Achieve precise particle removal and ensure sterile filtration of your samples
Confidently remove particles and impurities to protect your samples and ensure consistent, high-quality results. Sartorius offers a broad selection of filtration solutions that streamline sample preparation, safeguard analytical accuracy, and support sterility across a wide range of volumes.
Whether you're preparing reagents, clarifying buffers, or performing sterile filtration, our user-friendly devices help reduce risk, save time, and ensure process reliability from start to finish.
Critical tools for preparing and designing 2D/3D cell-based assays
Maintaining cell integrity and preventing contamination are essential for the success of 2D and 3D cell-based assays. Sartorius supports you at every step—from using proper pipetting techniques for consistent 3D cultures to providing ultrapure water that protects against harmful ions, organics, and microbes.
Our solutions help you optimize assay conditions for sensitivity and specificity, ensure cell health, and streamline contamination control with rapid testing kits. From reliable transfection reagents and growth factors to trusted cell culture media, we provide the tools you need to achieve reproducible, high-quality results.
Solutions
Maximize Chromatography Accuracy Through Reliable Sample Preparation Solutions
Accurate and consistent chromatography starts with effective sample preparation. From concentrating analytes to removing particulates, each step plays a vital role in ensuring high-quality results, protecting your instruments, and optimizing lab efficiency.
Sartorius provides trusted solutions to support every part of the process—from ultrafiltration and ultrapure water to precise weighing, ergonomic pipetting, and reliable filtration. Our tools help you streamline workflows, reduce variability, and maintain the integrity of your samples for reproducible and confident chromatography outcomes.
Solutions
Enhance the sensitivity and specificity of molecular assays, allowing for the detection of low-abundance targets with high-quality sample preparation.
Ensure rapid, reliable protein and nucleic acid sample preparation to support high-quality downstream analytics and assays. Sartorius offers end-to-end solutions to streamline workflows—from fast protein and virus harvesting to precise concentration, purification, and contamination-free pipetting.
Our ultrafiltration devices, RNase-/DNase-free ultrapure water systems, and DNA extraction kits help eliminate inhibitors and protect sample integrity. Combined with consistent blotting membranes and smart, ergonomic pipetting tools, these solutions empower you to generate reproducible results with confidence across molecular biology, PCR, CRISPR, and other demanding applications.
Solutions
Explore Our Portfolio for Sample Preparation
Sartorius Products Proudly Feature:
Accurate weighing, pipetting and processing minimizes the risk of introducing errors or biases. This leads to more accurate and interpretable data, which is crucial for drawing valid scientific conclusions.
- Seamlessly integrate your workflow with our smart, connected electronic pipettes.
- Arium® Ultrapure Water Systems ASTM Type 1 water increases the sensitivity of analytical results and minimizes chemical ion interference
- Cubis® High Capacity Micro Balance enables the highest accuracy
- Outstanding instrument performance: We ensure your devices operate at peak performance over the entire instrument life cycle.
- Reliable Results: Regulatory compliance and audit security results backed by our ISO/IEC 17025 accredited calibration laboratories.
- Global Presence: Over 60 service locations worldwide and more than 500 service experts ensure timely assistance.
Sustainability is one of our 3 core values and we follow multiple strategies to increase circularity of our lab instruments and consumables. Here are some examples:
- Reduce: We are reducing the amount of packaging materials where possible. For example, the packaging size of the Sartolab® RF|BT 150-250 ml product variants was reduced between 11% (cardboard packaging) and 22% (plastic packaging film).
- End-of-Life and Recyclability: To enable high recycling rates, our instruments are typically easy to disassemble. For example, the Quintix® Pro lab balance avoids using restrictive technologies, like adhesives, to simplify the recycling process.
- The Optifit Tip Refill Tower offers a variety of tip volumes in a space-saving package for a wide range of laboratory applications. It reduces plastic consumption and logistics emissions. In addition, the Refill Tower packaging has earned the ACT label.
Resources for Sample Preparation
Frequently Asked Questions
Proper sample preparation is crucial for minimizing variability, enhancing detection sensitivity, and strengthening the credibility of scientific research. It ensures that samples are reproducible and precise, leading to accurate and reliable experimental results.
Remember to use filtered tips to minimize cross contamination risk, and utilize reverse pipetting mode for viscos liquids to improve accuracy and repeatability.
Typically creating larger batch of master mix is more efficient and can improve the repeatability of assays.
For more tips, see Pipetting Academy Sample Preparation module.
Sartorius filtration products, such as Minisart® syringe filters and Sartolab® vacuum filtration units, are designed for precise particle removal and sterile filtration.
They help achieve accurate and reproducible results by removing impurities and ensuring sample sterility.
Sartorius enhances the sensitivity and specificity of molecular biology assays with high-quality sample preparation solutions, including ultrafiltration devices, ultrapure water systems, and extraction kits.
These products allow for the detection of low-abundance targets and ensure reliable results.
For critical analyses in analytical research where a low organic content is required (e.g. HPLC or ICP-MS), a water purification system that includes a UV-lamp is needed. After the UV-lamp, a deionization cartridge is needed to remove the ions that have been oxidized.
Additionally, it is highly recommended to use activated carbon because of its high surface area and adsorption properties that allow it to efficiently remove organics from the product water.
This is usually achieved by using a mixed bed resin cartridge that contains both deionization resin and activated carbon after the UV-lamp instead of a pure deionization resin cartridge.
The final TOC value, however, is completely dependent on your feed water. If your feed water has a high initial TOC value, you will need to pretreat it first, otherwise you may not be able to achieve the low TOC value you need.
In addition, the higher value TOC that goes into the system, the faster you will exhaust the consumables, leading to shorter change intervals and higher total cost of ownership.
Online literature, papers and research forums are a good source of application information.
However, for specific advice on filtration methods across a range of application workflows, Sartorius has an extensive range of test data, technical guides and application notes and are available to contact for advice and workflow queries.
Further, product samples or demonstrations are often available free of charge to help users confirm the optimal lab filtration processes.
Explore our Laboratory Ultrafiltration Product Qualification Guide.