Consistent Product Recovery No Matter What
Get the maximum product yield using our unique Hydrosart® membrane technology. Benefit from a chemically resistant cellulose membrane. It ensures the highest product recovery even under harsh process conditions.
Save up to 3 hours from your UF|DF processing time using our unique cassettes and advanced crossflow system engineering.
Crossflow Cassettes and Systems for Highest Product Yields
Hydrosart® Cassettes for All Applications
The Most Resistant
Spend less time cleaning, sanitizing, steaming, and sterilizing. Our Hydrosart® cassettes use a unique membrane that has the highest chemical resistance, temperature stability and gamma compatibility. The Hydrosart® UF | DF cassette is the perfect fit for mAb, blood & plasma, vaccines and ADC processes.
Scalable Results with SARTOFLOW® Systems
Rapid Process Development
Operators using our configurable SARTOFLOW® crossflow systems benefit from a modular platform. Use the same automation, user interface, data acquisition and process analysis tools from process development to commercial manufacturing. Mitigate the risk of operator error and significantly reduce your development time in both single-use or multi-use processes.
Find Out Why Hydrosart® Crossflow Membranes are so Productive
Crossflow Filtration (also known as Tangential Flow Filtration, or TFF) is a filtration method used under dynamic flow conditions. Product feed flows tangentially along the surface of the membrane where the product molecule is retained, while buffer and contaminants pass through the membrane. Sartorius Crossflow Ultrafilters contain Hydrosart TFF Membranes of various molecular weight cut-offs to manage volume reduction and buffer exchange in antibody, vaccine, and blood & plasma processes. Hydrosart is the preferred and best performing TFF membrane for biopharmaceutical manufacturing.
Speed Up with Single-Use Crossflow Solutions
Single-use crossflow solutions are the key technology in fast and reliable downstream processing of biopharmaceutical products. Using a pre-sanitized, sterile single-use crossflow device enables the reduction of process steps, labor costs and buffer or WFI usage significantly.
The High Throughput Solution for Parallel Screening
ambr® crossflow provides at early development stages access to molecule behavior related to viscosity, buffer composition, shear stress and performance in membrane processes. It enables a lot of important additional decision criteria for the final candidate selection and speeds up this process significantly.
Smart and Easy – The Crossflow System for Process Development
The ideal benchtop crossflow system for your process development and for small batch production in cGMP environments. Receive highest product yields with the low shear membrane pump.
SARTOFLOW® Smart offers excellent flexibility. It is ideal for membrane surface areas from 50 cm² to as much as 0.14 m². Try the new Sartocon® Slice 50 ready to use 50 cm² crossflow device which can easily be interfaced with the SARTOFLOW® Smart system. It is ideally suited for membrane screening, available in a wide variety of MWCO’s and membrane polymers.
Everything for Your Setup
Choose the Right Crossflow Cassettes
Every crossflow step in your biopharmaceutical process requires constant quality, batch-to-batch consistency and high performance filtration. With our crossflow cassettes we ensure maximum product yield in all required steps. Our wide product portfolio offers solutions for single-use or multiple-use and guarantees a linear scale-up.
Holders and Accessories
The family of Sartorius crossflow filter holders features the latest advances in crossflow design for full flexibility. This unique design within the Sartocon® family provides you with predictable performance from process volumes down to scaling studies or in daily lab work.