TakeOne® Aseptic Sampling Solutions

Preassembled, Presterilized, Single-Use: For Simplified Sampling

Aseptic sampling is a principal component of an effective microbial control program. Samples collected with TakeOne® are used to measure critical purity attributes, such as bioburden and endotoxin levels, as well as important process parameters, such as metabolites, nutrients, osmolality, pH and more. TakeOne® aseptic sampling solutions have been designed to integrate seamlessly with stainless steel or single-use processes. 


Sampling devices arrive individually packed, preassembled, gamma-sterilized and ready for immediate use.

Fully Scalable

Samples can be taken in a variety of containers, including bags, bottles, tubes and syringes, and in a range of R&D- and manufacturing-scale volumes.

Operator-Friendly Ergonomic Designs

Easy connection and disconnection mechanisms facilitate sampling procedures and increase processing efficiency.

Find the Right Sampling Solution

TakeOne® sampling solutions were designed to meet the sampling requirements of today’s varied manufacturing approaches. They can be used to obtain samples from stainless steel reactors and vessels or single-use systems and assemblies, providing cost-effective and technically robust solutions for all microbiological and routine process monitoring assays. An array of bags, bottles and tubes are designed to preserve the aseptic integrity of the source from which the sample is taken.


TakeOne® PDSTakeOne® Flex

Equipment Type

Stainless steel

Stainless steel*

Connection Type

1.5" and 2" sanitary ports
25 mm safety port (multiple lengths)

AseptiQuik® S single-use genderless aseptic connector

Disconnection Type

Quickseal® 1/8" x 1/4" aseptic disconnector**

Quickseal® 1/8" x 1/4" aseptic disconnector**

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* with TakeOne® Flex device
** others upon request

Sampling from Stainless Steel Equipment

TakeOne® Solutions for Stainless Steel Equipment

  • The unique device design integrates an aseptic chamber to ensure a closed fluid pathway, preventing any risk of microbial ingress.
  • 316L stainless steel face plate ensures compatibility with all stainless steel equipment.
  • Mounted at the tank interface ensures a representative sample and avoids dead legs.
  • Spring-loaded needle enables complete control of sample volumes and improves sampling accuracy.

Access process fluids in pressurized stainless equipment using Sartorius devices designed to fit commonly used ports.

  • Closed and aseptic sampling
  • Perfectly representative samples
  • Pre-assembled and ready-to-use or configurable at the point-of-use
  • On-demand sample collection
  • Operator-friendly ergonomic design
  • Fully single-use and disposable

Fully Closed and Independent Sampling Lines

25mm device with up to 3 sampling lines

1.5" device with up to 5 sampling lines

2" device with up to 9 sampling lines

How to Sample Using TakeOne® Devices 

Access process fluids in pressurized stainless equipment quickly, easily, accurately and safely.

Step 1 - Receive

Step 2 - Install

Step 3 - Sample

Step 4 - Disconnect

Step 5 - Remove

Step 6 - Safely Dispose

Break Process Bottlenecks with TakeOne® Devices

Engineered to take  representative samples for accurate results with no risk of false positives for every process step. A closed system design ensures process fluids can easily be collected for analysis while protecting the process from adventitious agents.

  • Pre-assembled
  • Pre-sterilized
  • 100% integrity tested
  • Curated selection of collection containers for reliable, repeatable assay results

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Increase Agility with TakeOne® Flex 

Sartorius’ solution allows you to react quickly on demand, while meeting all of your varied sampling needs. Decoupled devices and containers ease handling of complex equipment while allowing for process variability up until a sample is taken at the point of use. Select and connect the collection container of choice at the moment the sample is required.

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Fine-tune Your Sampling Solution with TakeOne® Design Services

TakeOne® design services leverage a wider variety of components, such as alternative tube materials and collection vessels, so you can modify standard features or build customized designs to match your unique requirements. Rely on Sartorius’ application-based expertise to help fine-tune your designs and optimize your process.

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Sampling from Single-Use Systems

TakeOne® for Single-Use Systems

A diverse collection of containers and sampling valves connect directly to single-use assemblies and systems via aseptic connectors or weldable TPE tubing, are suitable for all biopharmaceutical applications. Modular sampling solutions from Sartorius ease handling of complex process equipment and allow for variability with point-of-use connections.  This provides the highest degree of flexibility and adaptability for sampling and small-volume fluid handling. 

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Increase Agility with TakeOne® Flex Sampling Solutions

Avoid overwhelming your inventory management program. Maintain just a few SKU’s (stock keeping units) and create tens or hundreds of different sampling solutions for all of your single-use systems and assemblies.

TakeOne® Flex has a vast array of different single-use sampling options:

  • Bags
  • Bottles
  • Centrifuge tubes
  • Multi-use sampling valves
  • Manifolds of containers

A modular approach enables the use of standardized bag assemblies in a wider variety of applications by accommodating multiple types of containers.

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Fine-tune Your Sampling Solution with TakeOne® Design Services

Whether you need standard features adjusted or you require customized designs to match your unique requirements, TakeOne® design services leverage a wider variety of components, such as alternative tube materials and collection vessels, or add features and functionality. Rely on Sartorius’ application-based expertise to help fine-tune your designs and optimize your process.

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Related Products

Aseptic Connections 

Sartorius brings together multiple technologies and vast experience, with more than 1.2 million sterile connections supplied every year, we can help y...

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Aseptic Disconnections

Sartorius offers multiple disconnection technologies, with proven sterility assurance, to accommodate your specific process requirements.

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Learn More About TakeOne®

Featured Application Note

Selecting the Right Sample Collection Container

Not all samples are equal — categorization of a sampling plan by assay type reduces costs, improves sampling results and optimizes capacity of the sampling solution.

Download Application Note

Related Assets


TakeOne® - Design Services for Aseptic Sampling Solutions

PDF | 496.2 KB
White Paper

The Importance of Aseptic Sampling Devices in a Bioburden Reduction Strategy

PDF | 390.9 KB
Application Note

Aseptic Sampling Best Practices: Sample Collection for pH and Gas Analysis

PDF | 540.2 KB
Application Note

Aseptic Sampling Best Practices Endotoxin Binding Affinity

PDF | 457.8 KB

Consult Our Experts

Consult Our Experts

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