Microbial Bioreactors and Fermenters from PD to Commercial Manufacturing
Sartorius provides a specialized range of fermenters designed for microbial cultivation, meeting the specific requirements of microbial cultures, including high oxygen demand and effective management of metabolic heat.
With expertise in automation and engineering, Sartorius provides robust, scalable systems ensuring reliable control of culture conditions. The advanced analytical capabilities and intuitive usage support a Quality by Design approach, optimizing process design and its understanding.
While stainless steel bioreactors have been the traditional choice for larger -scale microbial applications, the biopharmaceutical industry's demand for flexibility has led to the rise of single-use solutions. Sartorius's portfolio includes innovative single-use bioreactors like the Ambr® 250, Biostat® RM and Biostat STR® Microbial, offering high performance and scalability as well as reliable seed train solutions from early product development to commercial manufacturing.
Sartorius offers a complete, harmonized, and scalable portfolio with working volumes ranging from 100 mL to 40 L.
Ambr® 250. High throughput system with easy-connect bioreactors and flexible software that enables to manage many more experiments at the same time while reducing the cost per experiment.
Biostat STR® Microbial with 40 L performs on the highest level with a kLa of 675 h-1 and an OD600 up to 280 in a 20h E. coli model process.
Biostat® RM. Simplifying single-use seed train solution in microbial applications.
Ensures robust and scalable processes with accurate sensors and reliable control mechanisms.
Microbial Bioreactors Portfolio
Find the Right Microbial Bioreactor for Your Application
| Biostat STR® Microbial | Biostat® B-DCU with Univessel Glass | Biostat® B with Univessel Glass | Biostat® RM | Ambr® 250 Modular | Ambr® 250 High Throughput | |
|---|---|---|---|---|---|---|
| Vessel working volume | 1 – 40 L | 1, 2, 5, 10 L | 1, 2, 5, 10 L | 1, 2, 10, 20, 50, 100, 200 L | 100 – 250 mL | 100 – 250 mL |
| No. of parallel cultivations | 1 | 6 | 2 | 1 - 2 | 2 - 8 | 12 - 24 |
| Automation Platform | Biobrain® | DCU | DCU | Biobrain® | Ambr® 250 Software | Ambr® 250 Software |
| GMP-ready | | (requires MFCS) | (requires MFCS) | | | |
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