Functional Profiling

Phenotype and function assays are critical for selecting the top clinical antibody candidates with the desired characteristics.

The iQue Advanced Flow Cytometry Platform supports cell-based assays, by detecting target proteins in their native conformation on the cell surface, which is a better indicator of in vivo behavior.

The iQue Advanced Flow Cytometry Platform lets you perform rapid multiplexed analysis of immune cell function through simultaneous analysis of cell-mediated cytotoxicity, cell health, function, activation, phenotyping and cytokine profiling.

Epitope Mapping: Rapidly detect and visualize epitope regions for hundreds of clones with high sensitivity, and validate your data with additional information on cell health and viability— all in one assay.

ADCC Assays: Discriminate between effector and different target cell populations in the same sample using multiplexed screening assays.

Resources for Functional Profiling

Featured Resources


ADCC Poster

Rapid Multiplexed Profiling of Antibody Dependent Cell Cytotoxicity

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Application Note

Learn how a high throughput, multiplexed, no wash assay was used to simultaneously measure antibody internalization, antibody specificity, and cell he...

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Pharmacological Characterization of the Antibody Drug Conjugate, Kadcyla, Using Live-Cell Analysis

Application Note

Pharmacological Characterization of the Antibody Drug Conjugate, Kadcyla®, Using Live-Cell Analysis

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Application Note

Intellicyt® Mouse Igg Type and Titer Assay Kit

 A Novel Solution to Expedite Antibody Discovery

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iQue®️ Advanced Flow Cytometry Platform brochure cover

Brochure: iQue®️ Advanced Flow Cytometry Platform

Advanced high throughput flow cytometry solution speeds up your entire workflow

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Mouse IgG TNT Fred Hutch Application Note

Researchers at Fred Hutch Cancer Center streamlined their antibody discovery workflow by utilizing the Intellicyt® Mouse IgG Type and Titer Assay Kit...

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