Membrane Chromatography

Ready-To-Use Membrane Chromatography

Save up to 70% Processing Time and Work Space

Sartobind® membrane technology allows you to shift from slow and oversized expensive columns to small, single-use capsules. These membrane adsorbers are ready to use and save you a lot of time: Switch to single-use chromatography and you'll be able to eliminate packing, cleaning and revalidation steps.

Now Sartobind® Scales up to 100 L of Membrane

As membrane chromatography processes grow in size, multiple Sartobind® cassettes of 0.8 or 1.6 L volume can now be used to accommodate the needed process scale. Sterile gamma irradiated versions allow for continuous manufacturing and products that cannot be sterile filtered.

Three different stainless steel holders are available for maximum membrane volumes of up to 20, 50, or 100 L. The fluid path within the cassettes is the same as for Sartobind® capsules, so process development and small scale data can be extrapolated to the new format. Scaling up has never been easier!

Sartobind® Cassettes

Remove Contaminants with Sartobind® Q and STIC®

75% Buffer Savings

Efficiently remove contaminants such as DNA, endotoxin, host cell proteins, and viruses up to 30 times faster with Sartobind® Q or STIC membrane adsorbers. With Sartobind STIC® you will remove contaminants even at high salt concentrations. You can save even more time and buffer by skipping the dilution of cation exchange pools.

Sartobind® Q

Sartobind STIC®


Sartobind® Q and S for Virus Capture

10 Times More Binding Capacity

Sartobind® Q and S membrane adsorbers offer binding capacities >10 times higher than resins when purifying viruses such as adenovirus, lentivirus and virus-like-particles (VLP) for use in vaccines.

Sartobind® Q

Sartobind® S

Aggregate Removal with Sartobind® Phenyl

Boost Your Single-use MAb Process

Benefit from buffer savings of 75% compared to resins. The large pores of Sartobind® Phenyl allow for a better accessibility of large molecules to the phenyl groups. Smaller membrane volume and less buffer results in considerable cost savings.

Sartobind® HIC Phenyl

Sartobind® 4 & 8 mm Capsules

Up to 50% Higher Binding Capacity

The void-volume-optimized capsules can display up to 50% higher dynamic binding capacity at 10% breakthrough than conventional absorber capsules. The new design features optimized flow channels, significantly reducing void volume, sharpening breakthrough curves and reducing elution volumes. The result for your practical operations is simply a greater safety against breakthrough and a significant improvement of the robustness of your process.

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A Step Forward with Sartobind® Sulfated Cellulose

Pandemic Ready Influenza Virus Production

Comparisons of Sartobind® Sulfated Cellulose (SC) to commercial resins (A, B) have shown significant higher binding capacity for virus particles.

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Large Scale Modular Membrane Chromatography Cassettes

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Virus Purification with Membrane Chromatography

PDF | 1.8 MB

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Membrane Chromatography as a Robust Purification System for Large-Scale Antibody Production

PDF | 294.4 KB

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Efficient Aggregate Removal from Impure Pharmaceutical Active Antibodies

PDF | 1.6 MB

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Everything for your Setup

Holders and Accessories

The family of Sartorius filter holders features the latest advances in design for full flexibility. Here you will find the right holder and accessories for performing your process with quality and success.

MidiCaps® Filter Holders

MaxiCaps® Filter Holders

Filter Integrity Tester

Sartobind® Goes Mobile

The App for Membrane Chromatography

The Sartobind® web app provides a useful selection and learning tools: Calculate your flow rate. Define your IEX by changing pH and IEP or browse the digital library by key words for scientific literature.

iOS

You Can Count on Our Support

Trust our comprehensive range of services for your membrane chromatography processes: We gladly assist you with tasks like process validation...

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