Ready-To-Use Membrane Chromatography
Membrane chromatography is a well-established technology in bioprocessing. It is routinely used in the capture of large particles such as viruses and viral vectors, as well as in polishing steps for the removal of DNA, HCPs and virus. One hallmark of membrane chromatography is high productivity, others are high throughput and cost saving.
Save up to 70% Processing Time and Work Space
Sartobind® membrane technology allows you to shift from slow and oversized expensive columns to small, single-use capsules. These membrane adsorbers are ready to use and save you a lot of time: Switch to single-use chromatography and you'll be able to eliminate packing, cleaning and revalidation steps.
Now Sartobind® Scales up to 100 L of Membrane
As membrane chromatography processes grow in size, multiple Sartobind® cassettes of 0.8 or 1.6 L volume can now be used to accommodate the needed process scale.
Sterile gamma irradiated versions allow for continuous manufacturing and processing of products that cannot be sterile filtered.
Three different stainless steel holders are available for maximum membrane volumes of up to 20, 50, or 100 L. The fluid path within the cassettes is the same as for Sartobind® capsules, so process development and small scale data can be extrapolated to the new format. Scaling up has never been easier!
Remove Contaminants with Sartobind® Q and STIC®
Boost Your Single-use MAb Process
Efficiently remove contaminants such as DNA, endotoxin, host cell proteins, and viruses up to 30 times faster with Sartobind® Q or STIC membrane adsorbers. With Sartobind STIC® you will remove contaminants even at high salt concentrations. You can save even more time and buffer by skipping the dilution of cation exchange pools.
Aggregate Removal with Sartobind® Phenyl
75% Buffer Savings
Benefit from buffer savings of 75% compared to resins. The large pores of Sartobind® Phenyl allow for a better accessibility of large molecules to the phenyl groups. Smaller membrane volume and less buffer results in considerable cost savings.
Sartobind® for Virus Removal
Webinar on Platforming Antibody Drug Conjugate
Single-use manufacturing technologies allow companies to quickly bring cGMP manufacturing capability online with less capital investment. In the webinar, we describe a robust and scalable platform for ADC process development and manufacturing that uses single-use technologies to accelerate development timelines and increase manufacturing predictability while decreasing scale up risks. In addition, case studies on membrane chromatography and crossflow filtration will be presented and the chemical compatibility of the materials described in the platform to solvents typically used in ADC process will be discussed.