10x Faster Aseptic Filling with Single-Use Plug and Play Setup

Minimize filling time with an efficient aliquoting solution that pumps fluid to 10 bags simultaneously.

The Linkit® AX Aliquoting Solution is ideal for aliquoting small quantities of process fluids - fast, evenly, and reproducible batch-to-batch. The plug & play concept, combined with ready-to-use patented manifold design, minimizes operator effort and error and consistently distributes fluid between the 10 bags with an accuracy of ±5%. The solution is designed to address the pain points of manual filling and aliquoting applications without the need to heavily invest in big and complex equipment.

The Smart Aliquoting Solution

Watch how aliquoting can be simplified with the Linkit® AX Solution

Reach Higher Throughput

Fast filling performance with a unique flow-through fluid design of the main hub.

Work Confidently With More Automation

QApp guides the operator during a filling operation, ensuring batch-to-batch repeatability.

Simplify Aliquoting Operations

Fully assembled, compact and small footprint solution - no need to handle bulky and complicated traditional manifolds.

Go Paperless With Compliant Batch Records

Full end-to-end traceability in compliance to FDA directive 21 CFR part 11 and EU Annex 11.

Simplify Aliquoting

There is no product like the Linkit® AX in the market today

Aliquoting is a common task in bioprocessing - often done manually, with all the pain points that accompanies the use of traditional bag manifolds: bulky, difficult to handle & manipulate and prone to operator error.

Fully automated aliquoting systems require considerable capital investment and are more suited to drug substance and drug product filling applications.

The Linkit® AX aliquoting system is the first simultaneous filling solution, offering fast filling with a distribution accuracy of ±5.1% and not requiring an initial high capital expenditure cost.


Traditional Bag Manifold

Linkit® AX

High-End Automated Filling System











Plug and Play






Operator Effort




Filling Time for 50 L Batch

6 Hours

30 min

1 - 2.5 Hours

Manual Aliquoting vs. The Linkit AX® Solution: A Side by Side Comparison

Watch our video to see the innovative ways Linkit AX® is designed to simplify and speed up your aliquoting process.

Featured Assets

White Paper

Optimized Aliquoting for Robust Cell and Gene Therapy Processes

Read about the challenges associated with liquid handling in cell and gene therapy processes and the introduction of novel solutions that simplify ali...

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Success Story

Leading Biopharma Uses Linkit® AX: Here are the Results

Over 10x faster. Less errors. Sustainable Scaleup. Read about the real results this large biopharma achieved using Linkit® AX.

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Application Note

Speed up aliquoting operations thanks to Linkit(r) AX without compromi...

Learn which factors are significantly impacting accuracy and how to optimize them

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Linkit® AX Aliquoting Solution

Have a Closer Look

The Linkit® AX Aliquoting System consists of four elements:

  • Linkit® AX Single-Use Assembly
  • Pump to fill the bags
  • Cubis® II balance with QApp software to control the pump and the filling
  • Purge stand to position the purge system and inlet filling line correctly

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Linkit® AX Aliquoting Solution

Request Your Free Demonstration of Linkit® AX

Experience a new way of aliquoting.

Request a Demo

Integrating the Linkit® AX Into Your Process

The Linkit® AX Single-Use assembly is available with different configurations dependent on process needs.

The main processing unit has a fixed design, however certain options are available to choose from and inlets | outlets can be configured to meet and easily integrate any specific process requirements.

Linkit® AX

  1. Select Options
    ▪ Flexsafe® bag: 150, 250, 500 or 1,000 mL
    ▪ Purge system: Sartopore® Air MidiSart® 0.2 μm or 500 mL Flexsafe® bag
  2. Inlet | Outlet Process Configurations
    ▪ Inlet Linkit® AX to feed container
    ▪ Outlet 1 (and 2 on 1,000 mL Flexsafe® bag)

Sartorius offers a range of pre-designed Linkit® AX single-use assemblies. If the standard-to-order designs do not meet the process requirements, our extensive component library in the configure-to-order space or our design experts can tailor solutions to meet them.

Learn More About Linkit® AX

FAQs – Linkit® AX Aliquoting System

150, 250, 500 and 1,000 mL Flexsafe® 2D Bags.

Yes, the Cubis® II Balance keeps 21 CFR part 11 compliant digital batch records that can easily be exported.

Opta® SFT, AseptiQuik®, ReadyMate, Kleenpak™ HT, Kleenpak™ Presto and plugs on TPE tubes, however if your process requires another type of connection, our design experts are here to assist you.

We've Got You Covered - Meeting cGMP Guidelines

Linkit® AX single-use assemblies are assembled in ISO 7 certified cleanrooms in accordance with applicable cGMP guidelines. Each system undergoes a variety of in-process quality inspections including 100% visual inspection and 100% leak testing (pressure decay) of the main distribution assembly hub and Flexsafe® bag chambers. To support you in your regulatory needs, specific documentation is available upon request:

  • Validation guide
  • Extractables guide
  • Instructions for use
  • Technical drawings
  • Inspection guide
  • Product Compliance Statement

In case additional testing is required, you can request your validation study via Confidence® Validation Services.

Consult Our Experts

Consult Our Experts

Complete Your Aliquoting Setup

Tuflux® Silicone and TPE Tubing

Benefit from low extractable profiles for both silicone and TPE tubing to transfer critical fluids across process steps.

Explore Tuflux® Silicone and TPE Tubing

Quickseal® Disconnectors

Quickseal® aseptic disconnectors simplify critical fluid management by making aseptic disconnection fast and secure.

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Tubing Sets & Assemblies

Single-use assemblies are essential in bio-manufacturing processes but their importance can be overlooked.

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