Octet® ProA Biosensors

For Determination of Antibody Concentration

  • Direct measurement of immunoglobulins (IgG)
  • Assay samples without centrifugation
  • Fast turnaround of results
  • Broad dynamic range
  • Correlates to HPLC
  • Direct measurement of immunoglobulins (IgG) 25ng – 2mg/mL

Octet® ProA biosensors are coated with Protein A and enable rapid antibody quantitation from crude lysates, cell culture supernatants and complex matrices. The direct quantitation assay format of the Octet® ProA biosensors provides ELISA data in less than 2 minutes and can be automated for high throughput screening efforts. Using an established pH-based regeneration protocol, the biosensors can be regenerated multiple times to provide a cost-effective and time-saving assay format.

Featured Publications

MAb Quantitation Protein A HPLC vs Protein A Bio-Layer Interferometry

Rapid, accurate and cost-effective quantitation of monoclonal antibodies (MAbs) is essential for bioprocessing.

Read Application Note

Quantitation of Fc-Fusion Protein in Cell Culture Supernatants

The cell line development group at Biogen IDEC needed a robust assay for the measurement of Fc-fusion protein (Protein 1) in crude cell culture supern...

Read Application Note
Enhanced Efficiency in Lot Release and In-Process Testing of Biologics cover

Enhanced Efficiency in Lot Release and In-Process Testing of Biologics...

Bio-Layer Interferometry (BLI) is an optical technique that analyzes the interference pattern of white light reflected from two surfaces: a layer of i...

Read White Paper

Octet® ProA Biosensors

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