Growth Factors and Cytokines
Sartorius offers a large variety of growth factors and cytokines for ex vivo cell culture. These raw and ancillary materials are widely used in the field of cell and gene therapy as well as regenerative medicine.
CellGenix® growth factors and cytokines combine a maximum of quality and safety with excellent performance due to state-of-the-art production, stringent quality control and expert regulatory support. We follow a strict animal-derived component-free (ADCF) policy to ensure maximum safety of our growth factors and cytokines.
FAQs - Growth Factors and Cytokines
Growth factors are signaling molecules that regulate cell proliferation, differentiation, and migration. "Cytokine" was first used to define a subset of growth factors influencing immune and hemopoietic cells. However, it is now clear that cytokines can act on many different cell types and have diverse effects on proliferation and differentiation. Therefore, "cytokine" is now used more broadly and interchangeably with "growth factor."
Cytokines are added to cell cultures to promote proliferation and to maintain cells in the desired state or lineage by regulating proliferation and differentiation.
Cytokines and growth factors ensure differentiation and proliferation of the cell(s) of interest. They are critical cell culture media components, particularly when serum-and animal-free conditions or defined media are required.
Growth factors bind to receptors on the surface of cells and initiate signaling cascades that ultimately up- or downregulate genes involved in cell proliferation and growth.