Cell Culture Media Optimization and Development

Cell Culture Media Optimization & Development

Maximize the Potential of Your Cell Line With Tailored Media

Choosing the right media improves your product quality, eases scale-up, and reduces time-to-market – but knowing which media to choose depends on your unique process.  At Sartorius, our team of experts works with you to understand your needs and deliver an optimized media formulation that’s tailored to your process. We help you maximize the potential of your cell line with our media optimization, development, and analytics backed by decades of industry experience. 

Find Out How Screening, Optimization and Development Services Compare To Match Your Needs.

Benchmarking Study 

Media Optimization ServiceMedia de novo 
Development Service
Comparability data from screening against proprietary media library

 

 

 

Ad-hoc experts-to-experts interactions and decision   
Improve your formulation based on current process conditions   
Gain insights with analytics and spent media analysis   
Benefit from a comprehensive development service from scratch   
Access to small quantities for in-house confirmation runs   

Ensuring media formulation scalability for further manufacturing use

 

 

 


Selecting the right cell culture media and feed usually involves screening and benchmarking multiple off-the-shelf culture media across several suppliers.  

With our extensive experience in cell culture technologies and media development, we offer expertise and resources to help you perform these routine studies. Select any chemically defined media and we can make sure it’s included. 

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Media optimization based on your needs 

Ensure full flexibility and control over your media and upstream process. 
Whether you want to improve titer or product quality, our spent media analysis gives the insight needed to get the most out of your system, and our integrated analytical testing services ensure you’ll meet your quality needs. 

Accelerate your time-to-market 

Understanding your process is key to streamlining development and reducing time-to-market. Your process parameters, cells, and cell culture media interact in unique ways to define the productivity and quality of the protein output.  

Our process-integrated media service helps you think differently about cell culture media in your upstream process, and see what benefits the right media can offer. 

Achieve the titer and product quality you need 

Our team works in-house to deliver optimized media that’s as unique as your process. 

  • We perform process optimization using our Ambr® bioreactor system. 
  • Our team shares and discusses the interim data. 
  • We confirm the optimized process in a benchtop bioreactor to ensure easy process transfer and scale-up.

Supporting services  

From cells, processes, and analytics to media development and manufacturing, we combine powerful spent media analysis with intelligent DoE and process simulations to reach your objectives in the most efficient way. 

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We offer targeted and efficient services for developing new and customized cell culture media and feeds.  

In close collaboration with you, we carefully choose individual target values for process performance based on your application – including titer, cell viability, concentration, and more. Following a streamlined workflow, we combine powerful spent media analysis with intelligent DoE and process simulations to meet your needs.  

All our media and feed products are chemically defined and animal-derived component-free. After development, we offer flexible solutions to bring your formulation to powder production.  We offer flexible packaging solutions for bioprocess liquid in single-use bags from 100 mL to 1000 L.
We have access to various cell lines available for development, including CHO, HEK, hybridoma, MDXK, BHK21, and more.   Our targets include protein production, viral, and viral vector production (Adeno-Associated Viruses (AAV) and Lentivirus (LV) production for gene and gene-modified cell therapy applications).

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Learn More About CCM Optimization & Development

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Request Your Sample | Raw Materials and Consumables

To help find the right materials and consumables for your needs, request a sample from our portfolio.

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Case Study

Fast-Paced De Novo Medium Development for a HEK293 Suspension Process

See how our comprehensive approach to media development enabled our client to achieve rAAV titers up to 400% higher than their competitors.

Download Case Study

Related Assets

eBook

A Comprehensive Guide to Finding the Right Cell Culture Media for Your Bioprocesses

PDF | 2.1 MB
White Paper

CHO Media Screening Success Using Benchmarking Studies

PDF | 2.3 MB
White Paper

The Value of Spent Media Analytics for Optimizing Cell Culture Performance

PDF | 779.0 KB
Brochure

Bioprocessing Media and Buffers - Solutions That Adapt to Your Needs

PDF | 1.6 MB
Application Note

How Spent Media Analytics Can Support Process Optimization

PDF | 340.0 KB

Related Services

Cell Line Adaptation & Cell Culture Adaptation

Let us help you scale up your process by overcoming adherent culture limitations and selecting the optimal animal component-free media.

Customized Media and Buffers

Robust and reliable production of customized cell culture media and buffers based on existing formulations or improvement of recipes.

Cell Line Development

Maximize the potential of your cell line using our reliable platform, proprietary technologies, and industry-leading instruments. 

Consult Our Experts

Consult Our Experts