Sartoclear® Depth Filter Cell Clarification and Contaminant Removal Technologies
Sartoclear® filters are cellulose-based depth filters developed for demanding clarification applications in the biotechnological and pharmaceutical industries.
*Custom/bulk order quotes are provided within 72 hours of request.
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Products (67)
Various device formats are available to serve you from first the steps, throughout clinical phases and up to large scale manufacturing while always keeping the same filter material.
Applications:
- Mammalian cell culture harvests
- Microbial lysates
- Removal of precipitates from sera and plasma
- Particle and colloid removal from process intermediates
- Media Filtration
Grade | Description | Application examples1 |
DL90 | Very coarse primary grade on top of a coarse secondary filter for filtrations with high solid concentrations | Primary clarification of mammalian cell cultures, insect cell cultures, microbial fermentations, vaccines |
DL75 | Pure cellulose pre-filter combined with a coarse secondary filter | Primary clarification of mammalian cell cultures, insect cell cultures, microbial fermentations, vaccines |
DL60 | Coarse primary grade with a secondary fine filtration grade for lower to moderate solid concentrations | Post-perfusion bioreactors, vaccines |
DL20 | Fine filtration grade combined with a standard bioburden reduction grade for the removal of particles | Post centrifuge mammalian cell cultures, post primary depth filtration, process precipitates |
DL10 | Fine filtration grade followed by an very tight secondary filter for the removal of high concentrations of small particles | Post centrifuge microbial (e.g. E. coli) lysates, post primary depth filtration step, process precipitates |
1 The listed examples are indicative and need to be confirmed by small scale tests |
Available Formats for Scale-up
Sartoclear® Caps are easy to use screening devices that help you to find the best grade for your application. All packages contains 3 units of the same grade and come with plug-in Luer adapters for the easiest possible exchange of filters.
Sartoclear® Depth Filter Midscale Cassettes are developed for scale-up filtrations with volumes between five to 10 liters (depending on the cell density).
Sartoclear® Depth Filter Cassettes are single-use filtration devices especially designed for biopharmaceutical clarification applications. The unique modular devices provide linear scalability from small to large scale processes. Three different sizes allow for a seamless adaptation to different process fluid volumes.
Sartoclear® Depth Filter Lenticular Modules are stackable depth filters for use in stainless steel housings, which are often used in large scale manufacturing facilities for biologicals.
The manifold set contains the inlet and outlet adapter plates for Sartoclear® Depth Filters as well as Sartobind® membrane adsorbers cassettes.
Sartopore® 2 is the industry standard of high-performance polyethersulfone (PES) liquid filters. A broad variety of different pore size combinations ensures highly economic and safe filtration performance. From single-layer high flow solutions to specific Mycoplasma retentive filters, Sartopore®2 perfectly adapts to your specific process needs.
Filter Holders are hydraulic clamping systems especially designed for the use of modular Sartoclear® Depth Filter cassettes and Sartobind® membrane chromatography cassettes. The holders are available in three standard formats for pilot scale and commercial manufacturing.
For serial or parallel filtration on one layer
Prevents excessive pressure during compressed air draining of the filter cassettes.
Filter Holders are hydraulic clamping systems especially designed for the use of modular Sartoclear® Depth Filter cassettes and Sartobind® membrane chromatography cassettes. The holders are available in three standard formats for pilot scale and commercial manufacturing.
For easy cleaning of spilled fluids
Filter Holders are hydraulic clamping systems especially designed for the use of modular Sartoclear® Depth Filter cassettes and Sartobind® membrane chromatography cassettes. The holders are available in three standard formats for pilot scale and commercial manufacturing.
For easy cleaning of spilled fluids