Sartocube® ECO Hydrosart® Cassette
Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications.
- Hydrosart® is stable across a broad pH range.
- Hydrosart® is extremely hydrophilic, making it non-protein binding, and virtually non-fouling.
- Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations.
These features make Hydrosart® an ideal membrane for biological applications.
Item no.: 3M21443935E-BSW
Availability: On Request
Hydrosart® ECO ultrafiltration cassettes allows high mass transfer at low feed flow rates. The following nominal molecular weight cut offs are available:
- 10 kD
- 30 kD
- 100 kD
- 300 kD
Hydrosart® 10 kD main applications are:
- Removal of contaminants
- Recombinant proteins
- Antibody fragment bio-conjugates
- Special mAb’s e.g. one heavy chain and 2 light chain mAb
Filtration Area3.5 m²
Flow Channel GeometryProtein conc. <20% /or viscosity max.3cp
Cassette FormatSartocube Cassettes
Maximum Inlet Pressure4 bar
pH StabilitypH 2 – 14
eShop Dynamic Attributes
Bacterial Endotoxins< 0.18 EU/mL as determined by the LAL test
BiosafetyAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Filter TypeCrossflow Filters
IndustryPharma / Biotech
Integral FramePolyvinylidene fluoride (PVDF)
Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
Sealing CompoundSilicone White (High chemical resistance)
The Sartoflow® 10 stainless steel holder with hydraulic is designed for crossflow applications from 30 L to 1000 L volume. The holder is optimised for the use with up to ten Sartocon® or two Sartocube® production scale crossflow cassettes (max. 7 m²). Typical applications of the Sartoflow® 10 holder are concentration and diafiltration of proteins, vaccines, antibodies, oligo nucleotides, endotoxin removal etc. and cell harvesting and clarification processes.
The Sartoflow® 20 stainless steel holder with hydraulic is designed for crossflow applications from 200 l to 2500 l volumes. The holder is optimized for use with 4 Sartocon® up to 20 Sartocube® production scale crossflow cassettes (max. 14 m2). Typical applications of the Sartoflow® 20 system includes concentration and diafiltration of proteins, vaccines, antibodies, oligo nucleotides, endotoxin removal etc., cell harvesting and clarification processes.