Full Flexibility Meets Outstanding TFF Performance
01. - 2.1 m² membrane sizes | 10 L stainless steel vessel or 5, 10, 20 L single-use bags for recirculation
High product yields
4-piston membrane pump for low shear
Two pumps for feed and buffer addition, as well as full TMP control
Item no.: SFADVANCED
Sartoflow® Advanced is suitable for flexible use in laboratory environments, for process development and clinical trials as well as for small-scale production batches. Several standardized options are available that can be upgraded with additional options if requirements change during process development or production.
This TFF system is equipped with the established DCU-4 control unit that readily communicates with BioPAT® MFCS software.
The System can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes, providing an exceptionally wide range of membrane surface areas. Since all Sartocon® TFF cassettes have the same hydrodynamic flow path length, the Sartoflow® Advanced can be linearly scaled up from 0.1 to 2.1 m² of membrane area. Its unique compact design has an ultra-low loop volume of ~200 mL, making it possible to concentrate even small process batches.
ApplicationPurification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
Dimensions WxDxH1,100 × 800 × 680 mm
Membrane Area0.1 - 0.5 m² (optionally 0.7 - 2.1 m²)
Tube Size (ID – OD)1/2"
- Standard Cassettes
- Sartocon Cassettes
Pump Output700 L/h @ 4 bar (60 psi)
Surface Roughness of Wetted PartsRa <= 0.6 µm
Materials of Construction
Recirculation VesselStainless steel 316 L
Maximum Operating Pressure4 bar (58 psi)
Minimum Operating Volume~200 mL
Power Requirements230 VAC | 50 Hz 2.5 Amp; 120 VAC | 60 Hz 4 Amp
Recirculation Vessel Volume10 L (MU)
VolumeBag: 5, 10, 20 L (SU)
Total Weight~ 120 kg