ambr® CF Filter Hydrosart® 10 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® crossflow system.

Catalog No.: 
3MA1443910
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

The Hydrosart® Membrane

Hydrosart® is a cross linked regenerated cellulose based membrane that has been optimized for the Biopharmaceutical industry. The Hydrosart® membrane is a robust polymer that can operate over a broad pH range. Hydrosart® is also extremely hydrophilic, making it non-protein binding and non-fouling. Membrane depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations. These features make Hydrosart® an ideal membrane for Biopharmaceutical applications.

Hydrosart® 10 kD main applications are:

  • Removal of contaminants
  • Proteins
    • Albumin
    • Hemoglobin
  • ADC
  • Recombinant proteins
  • Antibody fragment bio-conjugates
  • Special mAb’s e.g. one heavy chain and 2 light chain mAb

User Manual

Applications

  • Industry
    Pharma / Biotech

Dimensions

  • Filtration Area
    10 cm²
  • Flow Channel Geometry
    Screening Device

General Specifications

  • Cassette Format
    ambr® CF filter
  • Filter Format
    Cassettes
  • Ultrafilter
    10 kD Hydrosart® Ultrafilter

Materials of Construction

  • Membrane Material
    Hydrosart®

Operating Conditions

  • Maximum Inlet Pressure
    3 bar
  • pH Stability
    pH 2 – 14

Physicochemical Information

  • MWCO
    10 kD

Product Information

  • Brand
    Ambr® CF Filter
  • Filter Type
    Crossflow Screening Filters
Ambr® Crossflow - 4 channel system including control station

Study factors for manufacturability

Collect important information about the behaviour of the molecules in downstream processing already in an early stage

Automated, parallel trials

Up to 16 channels can be managed by one control station

Lowest process volumes

Small scale screening with 10 cm² membrane area | 5 mL recirculation volume

Flexibility of two different process scales

Mid-scale screening is also possible with Sartocon® Slice 50 which has 50 cm² membrane area

Ambr® Crossflow
Item no.
M_Ambr_Crossflow

Study factors for manufacturability

Collect important information about the behaviour of the molecules in downstream processing already in an early stage

Automated, parallel trials

Up to 16 channels can be managed by one control station

Lowest process volumes

Small scale screening with 10 cm² membrane area | 5 mL recirculation volume

Flexibility of two different process scales

Mid-scale screening is also possible with Sartocon® Slice 50 which has 50 cm² membrane area

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