Sartoclear® Depth Filter Cell Clarification and Contaminant Removal Technologies

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Sartoclear® Depth Filter Cell Clarification and Contaminant Removal Technologies Sartoclear® Depth Filter Cell Clarification and Contaminant Removal Technologies Sartoclear® Depth Filter Cell Clarification and Contaminant Removal Technologies Sartoclear® Depth Filter Cell Clarification and Contaminant Removal Technologies Sartoclear® Depth Filter Cell Clarification and Contaminant Removal Technologies
 

Sartoclear® filters, which are cellulose-based depth filters, have been specifically designed for challenging clarification tasks in the biotechnological and pharmaceutical sectors, with their primary applications being monoclonal antibodies (mAbs) and Adeno-Associated Virus (AAV) processes.

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Products (43)

  • Sartoclear® Cassettes 0.2 m²
    Sartoclear® Cassettes 0.2 m²
  • Sartoclear® Midscale Cassettes
    Sartoclear® Midscale Cassettes
  • Sartoclear® Cassettes 0.8 m²
    Sartoclear® Cassettes 0.8 m²
  • Sartoclear® Caps
    Sartoclear® Caps
  • Sartoclear® Cassettes 0.4 m²
    Sartoclear® Cassettes 0.4 m²
  • Sartoclear 12 Module, S020, FA-Adapt, 1pc
    Sartoclear 12 Module, S020, FA-Adapt, 1pc
    Item no.
    29LS020-12-FA
    Filtration Area
    1.9 m²
    Retention Rate
    0.2 µm
    Grade
    S020
    Filtration Layer
    Single layer
  • Sartoclear 16 Module, S200, FA-Adapt, 1pc
    Sartoclear 16 Module, S200, FA-Adapt, 1pc
    Item no.
    29LS200-16-FA
    Filtration Area
    3.7 m²
    Retention Rate
    2.0 µm
    Grade
    S200
    Filtration Layer
    Single layer
  • Sartoclear 16 Module, S080, FA-Adapt, 1pc
    Sartoclear 16 Module, S080, FA-Adapt, 1pc
    Item no.
    29LS080-16-FA
    Filtration Area
    3.7 m²
    Retention Rate
    0.8 µm
    Grade
    S080
    Filtration Layer
    Single layer
  • Sartoclear 16" Lenticular Module, DL10, FA-Adapt, 1pc
    Sartoclear 16" Lenticular Module, DL10, FA-Adapt, 1pc
    Item no.
    29LDL10-16-FA
    Filtration Area
    1.9 m²
    Retention Rate
    15 µm | 2.0 µm
    Grade
    DL90
    Filtration Layer
    Double layer
  • Sartoclear 16 Module, S010, FA-Adapt, 1pc
    Sartoclear 16 Module, S010, FA-Adapt, 1pc
    Item no.
    29LS010-16-FA
    Filtration Area
    3.7 m²
    Retention Rate
    0.1 µm
    Grade
    S010
    Filtration Layer
    Single layer
  • Sartoclear 16 Module, DL90, FA-Adapt, 1pc
    Sartoclear 16 Module, DL90, FA-Adapt, 1pc
    Item no.
    29LDL90-16-FA
    Filtration Area
    1.9 m²
    Retention Rate
    0.8 µm | 0.1 µm
    Grade
    DL10
    Filtration Layer
    Double layer
  • Sartoclear 12 Module, S400, FA-Adapt, 1pc
    Sartoclear 12 Module, S400, FA-Adapt, 1pc
    Item no.
    29LS400-12-FA
    Filtration Area
    1.9 m²
    Retention Rate
    8.0 µm
    Grade
    S400
    Filtration Layer
    Single layer
  • Sartoclear 16 Module, S020, FA-Adapt, 1pc
    Sartoclear 16 Module, S020, FA-Adapt, 1pc
    Item no.
    29LS020-16-FA
    Filtration Area
    3.7 m²
    Retention Rate
    0.2 µm
    Grade
    S020
    Filtration Layer
    Single layer
  • Sartoclear 16 Module, DL75, FA-Adapt, 1pc
    Sartoclear 16 Module, DL75, FA-Adapt, 1pc
    Item no.
    29LDL75-16-FA
    Filtration Area
    1.9 m²
    Retention Rate
    0.8 µm | 0.4 µm
    Grade
    DL20
    Filtration Layer
    Double layer
  • Sartoclear 12 Module, S200, FA-Adapt, 1pc
    Sartoclear 12 Module, S200, FA-Adapt, 1pc
    Item no.
    29LS200-12-FA
    Filtration Area
    1.9 m²
    Retention Rate
    2.0 µm
    Grade
    S200
    Filtration Layer
    Single layer
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    The Sartoclear® family is engineered from a trusted blend of cellulose and diatomaceous earth, providing a depth filter medium that has proven its effectiveness over time.

    Key Features:

    • Reliable Clarification: Depend on the Sartoclear® for effective biomass separation, utilizing the well-regarded method of normal flow depth filtration for proven success.
    • Ideal for screening up to commercial manufacturing: Discover the versatility of Sartclear® for all your processing needs, from screening to commercial manufacturing, with our range of five convenient sizes.
    • Quality Filtration Medium: The combination of cellulose and diatomaceous earth in the filter medium ensures a depth filter that consistently captures particulates, resulting in a clear filtrate.
    • Scalable Results: The Sartoclear® family is designed to provide scalable results, facilitating a smooth progression from small-scale and pilot processes to larger-scale production, ensuring a reliable pathway for process scaling.

    Applications:

    • Mammalian cell culture harvests
    • Monoclonal antibodies (mAbs)
    • Viral vectors (AAV; Adeno-associated virus)
    • Microbial lysates
    • Removal of precipitates from serum and plasma
    • Particle and colloid removal from process intermediates

    Double Layer Grades

    :
    • DL90 (First Layer: 15 µm, Second Layer: 2 µm): For primary (coarse) clarification.
    • DL75 (First Layer: 10 µm, Second Layer: 2 µm): For primary clarification, and in AAV clarification, it can serve as a single-stage solution followed by a sterilizing grade filter.
    • DL60 (First Layer: 8 µm, Second Layer: 0.8 µm): For primary or secondary clarification, and in some cases, as a single-stage clarification solution followed by a sterilizing grade (e.g., AAV clarification).
    • DL20 (First Layer: 0.8 µm, Second Layer: 0.4 µm): For secondary clarification post-depth filtration, -centrifuge or -perfusion.
    • DL10 (First Layer: 0.8 µm, Second Layer: 0.1 µm): For secondary clarification post-depth filtration, -centrifuge or -perfusion.

    Choose the Sartoclear® as your filtration solution to combine the reliability of proven techniques with the adaptability required for process development and commercial manufacturing. It represents the perfect balance between reliable results and convenient scalability.

    Discover the full Sartoclear

    ®

    product range in our eShop. Begin your path to scalable, efficient filtration excellence today – advance your bioprocessing with Sartoclear®.

  • Manifold Set for Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Manifold Set for Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Item no.
    29Z-S00001

    The manifold set contains the inlet and outlet adapter plates for Sartoclear® Depth Filters as well as Sartobind® membrane adsorbers cassettes.

  • Drip Pan for Process Filter Holder and Double Process Filter Holder
    Drip Pan for Process Filter Holder and Double Process Filter Holder
    Item no.
    2ZGL--0015

    For easy cleaning of spilled fluids

  • Process Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Process Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Item no.
    2ZGL--0006

    Filter Holders are hydraulic clamping systems especially designed for the use of modular Sartoclear® Depth Filter cassettes and Sartobind® membrane chromatography cassettes. The holders are available in three standard formats for pilot scale and commercial manufacturing.

  • Double Process Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Double Process Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Item no.
    2ZGL--0007

    Filter Holders are hydraulic clamping systems especially designed for the use of modular Sartoclear® Depth Filter cassettes and Sartobind® membrane chromatography cassettes. The holders are available in three standard formats for pilot scale and commercial manufacturing.

  • Sartoclear® Separation Plate
    Sartoclear® Separation Plate
    Item no.
    2ZGL--0013

    For serial or parallel filtration on one layer

  • Drip pan for Pilot Filter Holder
    Drip pan for Pilot Filter Holder
    Item no.
    2ZGL--0008

    For easy cleaning of spilled fluids

  • Pilot Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Pilot Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers
    Item no.
    2ZGL--0005

    Filter Holders are hydraulic clamping systems especially designed for the use of modular Sartoclear® Depth Filter cassettes and Sartobind® membrane chromatography cassettes. The holders are available in three standard formats for pilot scale and commercial manufacturing.

  • Pressure Safety Device
    Pressure Safety Device
    Item no.
    2ZGL--0014

    Prevents excessive pressure during compressed air draining of the filter cassettes.

  • Sartopore® 2
    Sartopore® 2
    Item no.
    M_Sartopore_2

    Sartopore® 2 is the industry standard of high-performance polyethersulfone (PES) liquid filters. A broad variety of different pore size combinations ensures highly economic and safe filtration performance. From single-layer high flow solutions to specific Mycoplasma retentive filters, Sartopore®2 perfectly adapts to your specific process needs.