CIMmultus® is a unique and industry-proven line of pre-packed chromatographic monolithic columns featuring large flow-through channels, which make them ideal for purifying large biomolecules such as viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), nucleic acids (mRNA, pDNA), virus-like particles and exosomes.

Without the need for column packing, CIMmultus® columns are ready for use out of the box.

Available in:

  • Varied monolith volumes
  • Wide range of CIM® chemistries
  • Differing channel sizes

See more Products below

*Custom/bulk order quotes are provided within 72 hours of request.

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Products (227)

  • CIMmultus® OH 40 mL Monolithic Column (2 µm)
    Item no.
    614.8140-2
    Ligand
    OH (hydrophobic, hydroxyl)
    Channel Size
    2 µm
    Bed Volume
    40 mL
    Package Type
    Individually Packed
  • CIMmultus PrimaS® 800 mL cGMP Compliant Monolithic Column (2 μm)
    Item no.
    921.5118-2
    Ligand
    Multimodal (anion exchange-hydrogen bonding)
    Channel Size
    2 µm
    Bed Volume
    800 mL
    Package Type
    Individually Packed
  • CIMmultus PrimaS® 80 mL Monolithic Column (2 μm)
    Item no.
    611.5118-2
    Ligand
    Multimodal (anion exchange-hydrogen bonding)
    Channel Size
    2 µm
    Bed Volume
    80 mL
    Package Type
    Individually Packed
  • CIMmultus PrimaS® 40 mL Monolithic Column (2 μm)
    Item no.
    614.5118-2
    Ligand
    Multimodal (anion exchange-hydrogen bonding)
    Channel Size
    2 µm
    Bed Volume
    40 mL
    Package Type
    Individually Packed
  • CIMmultus PrimaS® 400 mL Monolithic Column (2 μm)
    Item no.
    814.5118-2
    Ligand
    Multimodal (anion exchange-hydrogen bonding)
    Channel Size
    2 µm
    Bed Volume
    400 mL
    Package Type
    Individually Packed
  • CIMmultus® OH 4000 mL cGMP Compliant Monolithic Column (2 µm)
    Item no.
    934.8140-2
    Ligand
    OH (hydrophobic, hydroxyl)
    Channel Size
    2 µm
    Bed Volume
    4000 mL
    Package Type
    Individually Packed
  • CIMmultus® OH 800 mL Monolithic Column (2 µm)
    Item no.
    811.8140-2
    Ligand
    OH (hydrophobic, hydroxyl)
    Channel Size
    2 µm
    Bed Volume
    800 mL
    Package Type
    Individually Packed
  • CIMmultus® OH 400 mL cGMP Compliant Monolithic Column (2 µm)
    Item no.
    924.8140-2
    Ligand
    OH (hydrophobic, hydroxyl)
    Channel Size
    2 µm
    Bed Volume
    400 mL
    Package Type
    Individually Packed
  • CIMmultus® SO3 4000 mL cGMP Compliant Monolithic Column (6 μm)
    Item no.
    BIA-934.6157-6
    Ligand
    SO3 (strong cation exchanger, sulfonate)
    Channel Size
    6 µm
    Bed Volume
    4000 mL
    Package Type
    Individually Packed
  • CIMmultus® OH 1 mL Monolithic Column (6 µm)
    Item no.
    311.8140-6
    Ligand
    OH (hydrophobic, hydroxyl)
    Channel Size
    6 µm
    Bed Volume
    1 mL
    Package Type
    Individually Packed
  • CIMmultus® SDVB 40 mL Monolithic Column (2 μm)
    Item no.
    614.9001-2
    Ligand
    SDVB (reverse phase, poly(styrene-co-divinylbenzene))
    Channel Size
    2 µm
    Bed Volume
    40 mL
    Package Type
    Individually Packed
  • CIMmultus® SDVB 400 mL Monolithic Column (2 μm)
    Item no.
    814.9001-2
    Ligand
    SDVB (reverse phase, poly(styrene-co-divinylbenzene))
    Channel Size
    2 µm
    Bed Volume
    400 mL
    Package Type
    Individually Packed
  • CIMmultus® DEAE 8 mL cGMP Compliant Monolithic Column (2 μm)
    Item no.
    901.5114-2
    Ligand
    DEAE (weak anion exchanger, diethylamino)
    Channel Size
    2 µm
    Bed Volume
    8 mL
    Package Type
    Individually Packed
  • CIMmultus® QA 4000 mL cGMP Compliant Monolithic Column (6 μm)
    Item no.
    BIA-934.5113-6
    Ligand
    QA (strong anion exchanger, quaternary amine)
    Channel Size
    6 µm
    Bed Volume
    4000 mL
    Package Type
    Individually Packed
  • CIMmultus® SDVB 8 mL cGMP Compliant Monolithic Column (2 μm)
    Item no.
    901.9001-2
    Ligand
    SDVB (reverse phase, poly(styrene-co-divinylbenzene))
    Channel Size
    2 µm
    Bed Volume
    8 mL
    Package Type
    Individually Packed
  • Results per page: | |

    CIMmultus® Monoliths are reusable chromatography devices for scalable high-resolution purification of complex biological samples. Inside the custom-designed housing is a single-piece stationary phase with homogeneous channel size and surface chemistry. This stationary phase is designed to simplify method transfer from development into production.

    Features

    • Available with a wide range of chemistries
    • Various channel size options
    • Scalable from 1 mL to 40 L
    • Single batch use or multiuse
    • cGMP compliant

    Benefits

    • Very fast processes by convective mass transport – resolution independent of flow
    • Ready to use columns
    • High-capacity for large molecules due to fully accessible void volume in the channels
    • Laminar flow minimizes shear stress resulting in high yields

    Product Information

    • Brand
      CIMmultus®