Octet® AMC Biosensors

For Immobilization and Subsequent Kinetic Characterization of Mouse IgGs and other Fc-Containing Proteins

  • Complete kinetic analysis (ka, kd, KD) between mouse Fc-containing proteins and target analytes
  • Off-rate ranking of hybridoma and stable cell-line supernatants
  • Epitope binning/mapping (from crude or purified samples)

Octet® AMC biosensors enable kinetic characterization of macromolecular interactions between mouse Fc-containing proteins and target analytes.

Immobilization of mouse Fc-containing proteins is achieved through a factory immobilized anti-mouse Fc-specific antibody whose high-affinity for the mouse Fc domain provides the stable baseline required for demanding kinetics applications. Octet® AMC biosensors can be regenerated up to 10 times via a standard low-pH protocol in as little as two minutes for select applications.

Featured Publications

Enhanced Efficiency in Lot Release and In-Process Testing of Biologics cover

Enhanced Efficiency in Lot Release and In-Process Testing of Biologics...

Bio-Layer Interferometry (BLI) is an optical technique that analyzes the interference pattern of white light reflected from two surfaces: a layer of i...

Read White Paper

Octet® AMC Biosensors

Order Now

Additional Resources

Related Products

icon-multiple-biosensors

Octet® AMQ Biosensors

For Determination of Antibody Concentration

Explore More
icon-multiple-biosensors

Octet® AHQ Biosensors

For Determination of Antibody Concentration

Explore More
icon-multiple-biosensors

Octet® AHC Biosensors

For Label-Free Immobilization and Subsequent Kinetic Characterization of Human IgG or other Human Fc-containing Proteins

Explore More

Related Content

icon-octet-data-analysis-ht

Applications for Label-Free Detection

Explore More
icon-instrument-service

Octet® System Service and Support

Explore More
icon-supplement

Octet® BLI Resources

Explore More
Ready to Buy?