Powerful Media Filtration in Cell Culture Processes
Mitigate Your Risk
Filtration of cell culture media in biopharmaceutical manufacturing is largely driven by mitigating contamination risks and increasing product yield.
The requirements for media filtration are diverse, depending on the specific process set-up and the type of media:
- Protecting the cultivation process against any undesirable impacts
- Reaching a high process performance that is linked to increased yield
- Providing reliable and robust removal of bacteria, mycoplasma, or virus
To help you to optimize this process step, Sartorius provides a range of filters dedicated to filtration of cell culture media: Depending on the individual requirements, our toolbox contains filters for sterilizing-grade filtration (Sartopore® XLG), mycoplasma retention (Sartopore® XLM) or virus removal (Virosart® Media). For optimal and efficient removal of the bio-contaminants and process performance, these filters can either be combined, or a dedicated bioburden reduction filter can be added (e.g. Sartoguard PES).
To find the best working filter set-up for your process, your Sartorius Application Specialist will support you.
Sterile Media
High Speed Sterile Filtration with Sartopore® 2 XLG
Speed up your media preparation process using the Sartopore® 2 XLG sterilizing-grade media filter. You will benefit from the highest flow rate with our unique 0.8/0.2 µm membrane combination.
Mycoplasma-Free Media
High Retention and Capacity with Sartopore® 2 XLM
The Sartopore® 2 XLM is the most advanced 0.1 µm rated filter with the highest mycoplasma retention. The special membrane structure with narrow pore size distribution provides exceptional safety in retention of various mycoplasma. The highly asymmetric pre-filter membrane maximizes your filtration capacity and gives you the most economic media filter.
Virus-Free Media
Ultimate Virus Retention with Virosart® Media
Protect your cell culture media from virus contaminations with the tenfold tighter 20 nm Virosart® Media membrane. The filter retains ≥ 4 LRV for small non-enveloped viruses like MVM or Vesivirus and ≥ 6 LRV for large enveloped viruses.
