Powerful Media Filtration in Cell Culture Processes

Mitigate Your Risk

Filtration of cell culture media in biopharmaceutical manufacturing is largely driven by mitigating contamination risks and increasing product yield.
The requirements for media filtration are diverse, depending on the specific process set-up and the type of media:

  • Protecting the cultivation process against any undesirable impacts
  • Reaching a high process performance that is linked to increased yield
  • Providing reliable and robust removal of bacteria, mycoplasma, or virus

To help you to optimize this process step, Sartorius provides a range of filters dedicated to filtration of cell culture media: Depending on the individual requirements, our toolbox contains filters for sterilizing-grade filtration (Sartopore® XLG), mycoplasma retention (Sartopore® XLM) or virus removal (Virosart® Media). For optimal and efficient removal of the bio-contaminants and process performance, these filters can either be combined, or a dedicated bioburden reduction filter can be added (e.g. Sartoguard PES).
To find the best working filter set-up for your process, your Sartorius Application Specialist will support you.

Consult Our Experts

Sterile Media

High Speed Sterile Filtration with Sartopore® 2 XLG

Speed up your media preparation process using the Sartopore® 2 XLG sterilizing-grade media filter. You will benefit from the highest flow rate with our unique 0.8/0.2 µm membrane combination.

Learn More

Mycoplasma-Free Media

High Retention and Capacity with Sartopore® 2 XLM

The Sartopore® 2 XLM is the most advanced 0.1 µm rated filter with the highest mycoplasma retention. The special membrane structure with narrow pore size distribution provides exceptional safety in retention of various mycoplasma. The highly asymmetric pre-filter membrane maximizes your filtration capacity and gives you the most economic media filter.

Virus-Free Media

Ultimate Virus Retention with Virosart® Media

Protect your cell culture media from virus contaminations with the tenfold tighter 20 nm Virosart® Media membrane. The filter retains ≥ 4 LRV for small non-enveloped viruses like MVM or Vesivirus and ≥ 6 LRV for large enveloped viruses.

Learn More



Virus Risk Mitigation in Cell Culture Media

PDF | 527.9 KB
White Paper

Reducing Total Cost of Ownership in Media Filtration

PDF | 633.3 KB

Consult Our Experts

Consult Our Experts

Ready to Buy?