EpiAirway is a lab-grown human airway model for studying lung diseases, drug delivery, and inhalation toxicity - no animal testing needed.

Build Better Data with 3D Microtissues, Primary Cells, and Cultureware

Innovating In Vitro Science with MATTEK, now a Part of Sartorius

MATTEK, now a part of Sartorius, is a biotech company specializing in lab-grown human tissue models, primary human cells, and cultureware to support biomedical research and drug development. A global leader in engineered 3D in vitro human tissue models including skin, ocular, oral, respiratory, intestinal, and vaginal models. These models provide human relevant alternatives to animal testing with improved accuracy, reproducibility, and cost efficiency.

The portfolio includes not only ready to use microtissues like EpiDerm™, EpiAirway™, EpiAlveolar™, and EpiIntestinal™, but also primary human cells, specialized media, and optically superior cultureware (e.g., glass bottom plates and dishes) for high-quality imaging and in vitro assays.

Additionally, testing services, including advanced imaging and digital pathology tools for regulatory toxicology and efficacy studies across cosmetics, pharmaceutical, chemical, and household product industries, are performed in-house by Mattek's in vitro experts. Ensuring quality and regulatory standards are met, the tissue models meet OECD and EU testing guidelines and are widely used in the US, Europe, and Asia.
 

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Accelerate Your Research

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Human-Relevant Models

3D tissue models closely replicate human physiology, providing more predictive data than traditional 2D cultures or animal testing.

Improve Predictivity, Reproducibility, and Cost Efficiency

Ready-to-use microtissues and primary cells streamline workflows, enabling faster, more reliable drug screening, toxicity testing, and disease modeling.

Ethical and Regulatory Advantages

Validated in vitro models support regulatory compliance (OECD, EU guidelines) while reducing reliance on animal testing.

Integrated Imaging and Analysis

Advanced cultureware and imaging-compatible platforms enable high-resolution, real-time insights for reproducible and scalable results.

Discover the Cutting Edge of In Vitro Science

3D Microtissue Models

Explore living, metabolically active 3D human epithelial tissue models that enable both acute and long-term studies in a highly physiological in vitro environment.

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Cultureware

Cultureware blends the convenience of standard labware with the optical clarity of glass, optimized for high-resolution microscopy and long-term tissue culture. It serves as a foundational platform for accurate, reproducible imaging-based assays to support advanced in vitro research.

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Microtissue Toxicology Testing Services

Testing Services include advanced imaging and digital pathology tools for regulatory toxicology and efficacy studies across cosmetics, pharmaceutical, chemical, and household product industries. Their tissue models meet OECD and EU testing guidelines and are widely used in the US, Europe, and Asia.

Explore on MATTEK.com

Resources for Products and Research

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Poster

Integrated 3D Multi-Organ Plate for Real-Time Drug Toxicity Analysis

Explore a new 3D multi-organ tox plate with real-time analysis for faster, scalable, and animal-free drug toxicity testing.

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Advanced Cell Models Workflows

Techniques used to generate insight in biological processes utilizing advanced cell models

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Automated High-Throughput Selection and Picking of 3D Structures

Explore a workflow for automated scanning, detection and gating of complex 3D structures based on morphological and fluorescence parameters.

Frequently Asked Questions

A wide range of human-relevant 3D tissue models, including skin, eye, airway, intestine, vaginal, and oral epithelia - ideal for toxicology, drug screening, disease modeling, and regulatory testing.

3D tissue models better mimic human physiology, providing more predictive, reproducible, and ethical data while reducing reliance on animal models.

Yes. Many MATTEK models meet OECD guidelines and are accepted by regulatory agencies in the U.S., EU, and other regions for safety and efficacy testing.

High-quality human primary cells such as skin cells, airway cells and immune cells, specialized media, and glass-bottom cultureware are available. Used together, they have been optimized for live-cell imaging, long-term culture, and reproducibility.

Absolutely. Microphysiological systems from MATTEK, now a part of Sartorius, are metabolically active and robust, allowing for both acute and extended experiments in vitro.

Yes, custom tissue models and in-house testing services, including imaging and digital pathology can be tailored to your study needs.

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