In Vitro vs. In Vivo: Advancing Human-Relevant Testing Models

Last Updated: November 2025

Overview:

Animal models often fail to predict human outcomes, leading to costly trial failures and recalls. This white paper explores the shift toward advanced in vitro alternatives — such as 3D tissues, organoids, and organ-on-a-chip—that better replicate human biology. Learn how these models improve safety, efficacy, and regulatory compliance while reducing costs and eliminating ethical concerns.

Resource type: White Paper
Page Count: 8 pages
Read Time: 10 minutes


Key Takeaways:

  • Animal models often fail to predict human outcomes, causing costly trial failures.
  • Regulatory shifts encourage adoption of human-relevant in vitro methods.
  • Advanced models like 3D tissues, organoids, and organ-on-a-chip improve accuracy.
  • In vitro testing reduces costs, increases throughput, and eliminates ethical concerns.
  • OECD-approved guidelines validate these alternatives for safety and efficacy testing.

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