Incucyte® AI Nuclei Detection Software Module (Cat. No. BA-04897)
Accelerate your image-based research with the Incucyte® AI Nuclei Detection Software Module—an AI-powered solution for label-free segmentation of adherent cell nuclei from HD phase-contrast images. This purpose-built tool utilizes a pre-trained deep learning model to deliver high-accuracy nuclear detection without the need for fluorescent labels, dyes, or manual segmentation.
This module supports a broad range of applications, including label-free cell proliferation analysis, direct quantification of nuclear fluorescence for cell cycle and cytotoxicity studies, and detection of compound-induced changes in nuclear morphology such as nuclear swelling.
Compatible with all Incucyte® systems, this module simplifies and standardizes non-invasive cell analysis through a streamlined workflow, enabling researchers to objectively analyze cell health and proliferation across diverse experimental setups.
Incucyte® AI Nuclei Detection Software is available for purchase for all Incucyte® CX3 and S-Series instruments and requires software version 2025B or higher.
Incucyte® AI Nuclei Detection Software Overview
AI-Driven, Label-Free Nuclei Segmentation
The Incucyte® AI Nuclei Detection Software leverages deep learning to deliver accurate, label-free analysis of nuclei in high-resolution (HD) phase-contrast images.
This module offers:
- Precise segmentation of individual nuclei without the need for fluorescent labeling
- Pre-trained AI model—ready to use, with no additional training required
- Objective and reproducible results across adherent cell types up to high confluence
- Seamless integration into existing Incucyte® workflows for scalable analysis
- Designed for ease of use and robust performance, this module brings the power of AI to your cell imaging workflows—enhancing efficiency without compromising data quality.
Incucyte® AI Nuclei Detection Workflow
Incucyte® AI Nuclei Detection Analysis showing the resulting segmentation mask and nuclei count data.
AI Nuclei Detection uses a pre-trained neural network to segment the nuclei of live, adherent cells in Phase Contrast images. Nuclei masks are displayed and provide robust quantification of nuclei count and shape over time.
| Product | Qty. | Cat. No. |
| Incucyte® AI Nuclei Detection Software Module | 1 module | BA-04897 |
| available for Incucyte® CX3, SX5, S3, SX1 Live-Cell Analysis System. | ||
Incucyte® AI Nuclei Detection Software Features
- Leverage intelligent default settings powered by AI nuclei detection and pre-trained neural networks for accurate, non-invasive cell analysis.
- Detect nuclei reliably across a wide range of adherent cell types and confluency levels, enhancing data consistency throughout the full time course of your experiment.
- Quantify nuclear morphology metrics such as area, eccentricity, texture, and fluorescence intensity to support detailed cell health diagnostics using AI.
- Visualize and report results by generating customizable graphs and exporting high-quality images
