Case Study: Real-Time Insights with Live-Cell Analysis
Author: Jasmine Trigg, Scientist, Sartorius | Last updated: November 2024
Overview
Neurodegenerative diseases, including Parkinson's Disease (PD), are long-term and debilitating conditions that lead to the gradual degeneration and/or death of neuronal cells. Enhanced in vitro models that mimic the chronic nature of these diseases, along with advanced cell models like primary cells or induced pluripotent stem cells (iPSCs) in mono- or co-culture, can deepen our understanding of disease pathology and aid in drug discovery.
However, traditional methods used to study these dynamic biological changes present challenges. Investigating these complex and sensitive models necessitates advanced technologies, such as live-cell analysis, which can monitor and accurately quantify dynamic cellular processes in non-disruptive conditions.
- Document type: Case Study
- Page count: 4
- Read time: 5 minutes
Key Takeaways
- How live-cell analysis can be used to quantify changes in morphology, cell health, and function
- Quantitative Pharmacology in PD Co-culture Models
- Phagocytosis of Disease-Associated Peptides
Want the Full Application Note?
The above download is a case study generated from the application note, Live Cell Imaging: Kinetic Quantification of Neurite Dynamics in Mono-cultures and Co-cultures. Access below to explore this application in more depth.
