Sample Prep solutions for HPLC and more

Innovative Discovery: Fast and Simple

Sartorius' analytical sample preparation solutions combine our legendary quality and reliability with our design wisdom to provide the very best in high pressure liquid chromatography (HPLC), liquid chromatography–mass spectrometry, ion chromatography (LC-MS, IC), or inductively coupled plasma mass spectrometry (ICP-MS) filtration solutions.


  • Fast, simple, & economical
  • Low retention volumes & maximal recoveries
  • Almost zero leachables or extractables


Filter 8 Samples Simultaneously In Seconds!

Powerfully simple sample clarification for analytics, Claristep® Filtration Systems

Preparing samples by clarification is an essential step prior to nearly all analytical techniques, such as high pressure liquid chromatography (HPLC). That is essential maintaining the integrity of chromatography columns and for maximizing their operating life time. Today's instruments use smaller samples and have higher sensitivity so clarification devices need to have the lowest retention volumes and not contaminate experimental samples with leachables or extractables.

Sartorius has developed a new, easy-to-use and straightforward filtration system, expressly for HPLC and related systems. The manually operated Claristep® Filtration System consisting of a station and filter units offers a novel way for clarifying your samples with a number of advantages:

  • Fast & efficient, up to 8 samples simultaneously in seconds
  • Ergonomic design, almost zero leachables or extractables
  • EASY, & simple, no syringe required
  • Powerless, no need for a vacuum source or a power supply
  • Ideal for small samples (Volumes ranging from 60 μL to 600 μL)
  • Maximal recovery (Hold-up volume 30 μL)

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Clean up your Method!

Clean and Green Minisart® RC Syringe Filter solutions and other membrane options for sample preparation

Minisart® RC syringe filter devices from Sartorius are an excellent, environmental and eco-friendly alternative to PVDF devices. They are just as suitable, and often even better, for HPLC sample preparation than PVDF. The RC material is clean (nearly zero, leachables or extractables are extracted during filtration) and is all purpose and more convenient than PVDF. Minisart® NY with fast-flow polyamide membrane and the extremely versatile Minisart® SRP with hydrophobic PTFE round off the portfolio. If you're still using PVDF based syringe filters for HPLC sample prep, it is time to clean up your method! Switch to Minisart® filters: The better and cleaner solution - only from Sartorius.

  • Low adsorption of analytes
  • Maximum chemical compatibility
  • Minimum extractables or leachables

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Preparation of particle-containing and viscous food samples with the Claristep® filtration system

In food analytics, clarification by membrane filtration is often an important step in sample preparation for processes like HPLC. Designed for parallel processing of up to eight samples, the Claristep filtration system was examined to determine its suitability for the filtration of food samples. Fourteen commercially available food samples – among them very particle-rich dispersions – were filtered at various levels of dilution with the syringeless Claristep® 0.45 μm and 0.2 μm pore size filters.

Get Some Clarity in Analytical Sample Prep

Analytical Sample Prep Solutions optimized for Your Needs

Do you process dozens of samples each day? A syringeless solution will help you reduce time, effort and waste – and minimize hand stress. But, maybe you need to analyze only a few samples a day, or samples with volumes up to 200 ml? Then you will benefit from our proven combination of a syringe and syringe filter. The choice is all yours, but only from Sartorius!

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