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Integrated Single-use Solutions for the Manufacture of Biopharmaceuticals
Safety, flexibility and efficiency are playing an ever-increasing role in the manufacture of biopharmaceuticals. For this reason, demand is steadily rising for sterile single-use products and systems that connect these products easily, flexibly and safely. Configurable and scalable system solutions, such as Flexact®, can be used in all process steps – in preparation of media and buffers, cell harvesting, crossflow filtration, viral clearance, virus inactivation, polishing and in the form - fill and form - transfer process steps.
Cell Cultivation in Biopharmaceutical Processes
To enable cells to grow optimally in the production of active pharmaceutical ingredients, cells are cultivated in a bioreactor under controlled conditions. Important factors for cell growth include the composition of the nutrient medium, mixing efficiency, temperature, dissolved oxygen saturation and pH.
Analysis of Cell Culture Processes
Cell cultivation is initially tested at the lab-scale level. In trial series, the parameters of the individual samples are altered, such as pH, oxygen content and temperature, to find the conditions that are most conducive to optimal cell growth. During the cultivation process, the cultures are continually sampled and analyzed.
Ultrapure Water in the Lab
Type I reagent-grade water is essential in any laboratory and is used in nearly every lab procedure. Whether used to clean laboratory glassware, to prepare buffers and cell culture media or to perform critical laboratory applications, such as DNA sequencing, ultrapure water must have the appropriate degree of purity in order to ensure reliable research results.
Corporate Strategy, Human Resources Management, Legal & Compliance, Communications
Chairman of the Executive Board and CEO of Sartorius AG
Chairman of the Board of Directors and CEO of Sartorius Stedim Biotech S.A.
Finance, Information Technology, Global Business Processes
Member of the Executive Board of Sartorius AG