Octet® SPR HisCap Sensor Chip
Octet® SPR HisCap sensor chips consist of pre-immobilized nitrilotriacetic acid (NTA) within a nondextran polysaccharide 3D surface, which can be used for affinity capture coupling. In comparison to the strong interaction between streptavidin and biotin, the lower bond strength observed between NTA and a His-tag allows easy removal of His-tagged ligand proteins and regeneration of sensor chip surfaces using a variety of conditions, including imidazole, SDS and EDTA.
Top Features of the Octet® SPR HisCap Sensor Chip:
- High binding capacity
Popular Applications for the Octet® SPR HisCap Sensor Chip:
- LMW binding
Item no.: 19-0058
Octet® SPR sensor chips have been specifically designed to allow generation of robust and reproducible results for every application – from large molecules, molecular complexes, viruses or whole cells to small molecules or antibody fragments.
Octet® SPR HisCap sensor chips are ideal for small molecule, peptide or fragment kinetics and large molecule kinetic assays. They provide a reliable alternative for proteins unamenable to amine coupling.
- Low molecular weight binding