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Sartobind® S 75 mL, 4 mm bed height

Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.

Item no.:  96IEXS42D9MFF--A

Availability:  On Request


Sartobind® S membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Sulfonic acid ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates.


The S membrane adsorber is successfully used in FDA-approved drug manufacture to remove host cell proteins at high flow rates. As a cation exchanger it displays not only aggregate removal capabilities but typically at least ten-fold higher binding capacity for viruses and virus-like-particles (VLP).


The Sartobind S adsorber speeds up the production process by high flow rate and opens new opportunities for the purification of therapeutic proteins and vaccines.

  • High speed host cell protein removal up to 30 bed volumes/ min
  • Aggregate removal

Easy to use:

  • Plug and play devices from 0.08 ml to 5 l
  • Can be used like a filter
  • Flow rate up to 30 bed volumes/min
  • Disposable or re-usable

Application Note

Single-Use Membrane Chromatography in ADC Production
en 1.6 MB


Sartobind® Membrane Chromatography
en 2.8 MB


Sartobind® Q and S, 4 and 8 mm Bed Height
en 1.2 MB


Sartobind® Selection guide
en 1.0 MB

User Manual

Operating Instructions - Sartobind® Q and S - Void Volume Optimized Capsules and Cassettes With 4 | 8 mm Bed Height
en 3.0 MB

Compliance Information

  • Biosafety
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).


  • Bed Height
    4 mm
  • Membrane Area
    0.27 m²

Operating Conditions

  • Maximum Operating Pressure
    0.4 MPa
  • Maximum Venting Pressure
    0.5 bar, 0.05 MPa, 7 psi
  • Recommended Flow Rate
    1.5 L/min
  • pH Stability
    pH 3 – 14 (short term), pH 4 – 13 (long term)

eShop Dynamic Attributes

  • Application
  • Bed Volume
    75 mL
  • Connectors
    Sanitary ½ – ¾"
  • Housing Material
    Polypropylene (PP)
  • Ligand
    Sulfonic acid
  • Ligand Density
    2 – 5 µeq/cm²
  • Materials of Construction
    • Polypropylene, polyester
    • polyester
  • Membrane Adsorber Format
  • Membrane Material
    Stabilised reinforced cellulose
  • Membrane Type
    Strong cation exchange membrane
  • Pack Size
  • Pore Size
    3 – 5 µm
  • Reference Protein
  • Thermal Stability
    Sartobind capsules with ion exchange membranes can be autoclaved at 121 °C for 30 min. We recommend one autoclaving cycle only.
  • Type
    Membrane adsorber
  • Typical Dynamic Binding Capacity 10% per unit
    1.89 g
  • Void Volume
    180 mL
  • What you receive
    • 4 capsules
    • 1 operating instruction
    • 1 certificate
MidiCaps® Holder
MidiCaps® Holder
Item no.: 5ZGLG-0007

The Sartorius Stedim Biotech MidiCaps® holder has been specially designed to integrate MidiCaps® into biopharmaceutical processes.

Adapter Sanitary 25 mm 1/2-3/4" to UNF 10-32, polyoxmethylene.