Octet® SPR Sensor Chips and Consumables
Sensor chip selection is a critical feature of every Surface Plasmon Resonance (SPR) assay. From initial design and development to data acquisition and analysis, overall data integrity is influenced by initial sensor chip selection.
Each Octet® SPR sensor chip has been specifically designed to allow generation of robust and reproducible results for every application – from large molecules, molecular complexes, viruses or whole cells, to small molecules or antibody fragments.
Discover Octet® SPR with unique patented injection modes
Explore Octet® SPR Sensor Chips and Consumables
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Features of the Sartorius Octet® SPR Range
Robust and Reliable
- Exceptional sensitivity for small and large molecules, low baseline noise and drift, large injection volumes and novel OneStep® and NeXtStep™ Gradient Injection Technologies
- Generate high-quality kinetics and affinity data in a fraction of the time compared to standard multi-cycle kinetics
Accurate and Reproducible
- Each Octet® SPR sensor chip can be classified according to its immobilization matrix, binding capacity or type of bond formed with the ligand
- Irrespective of classification, each Octet® SPR sensor chip can help facilitate the generation of highly accurate and reproducible results across a variety of molecules and analyte complexes
Confidence and Maintenance
- Ensure total confidence in all results generated using the Octet® SF3 SPR platform
- Operational Qualification (OQ) provides documented evidence of platform performance
- The Octet® SPR Maintenance Reagent kit helps remove any absorbed proteins or other materials from the system and ensures long-term instrument performance
Explore the SPR Sensor Chips Collection
Octet® SPR COOH1 Sensor Chips
- Low binding capacity
- Matrix length from gold surface: ~2 nm
- Minimal distance between analyte and planar surface results in highly sensitive interactions
- Useful for large molecular weight analytes due to its matrix-free surface
- Can be used for whole cell, virus particle, multivalent or large analyte assays
Octet® SPR PCH Sensor Chips
- Highest capacity surface of all Octet® SPR sensor chips
- Matrix length from gold surface: 150 nm
- Useful for small molecules, fragments, organic molecules and low molecular weight compounds
- Can be used in experimental conditions not favorable to dextran polycarbonate surfaces
Octet® SPR CDL Sensor Chips
- Medium binding capacity
- Matrix length from gold surface: 50 nm
- Short dextran matrix
- Minimal distance between analyte and planar surface results in a highly sensitive interaction
- Intermediate (>1 kDa) - large (>25 kDa) molecules
- Can be used for whole cell or virus particle work
Octet® SPR CDH Sensor Chips
- High binding capacity
- Produces a highly stable covalent bond
- Matrix length from gold surface: 150 nm
- Small molecules: fragments and organic compounds
- Large molecules, viruses and proteins
- Biocompatible with a wide range of molecules
Octet® SPR Streptavidin Sensor Chips
- Medium to high binding capacity
- Senor chip surface has a lower electrostatic charge compared to amine sensors
- Intermediate (>1 kDa) - large (>25 kDa) molecules
- Controlled ligand orientation facilitates optimal analyte capture with low interference of the target ligand
- Validated for a broad range of applications
Octet® SPR HisCap Sensor Chips
- High binding capacity
- Suitable alternative for proteins not amenable to amine coupling
- Small molecule, peptide or fragment kinetics
- Stable baseline, important for accurate kinetic analysis
Octet® Surface Plasmon Resonance Resources
Octet® SPR Downloads and Guides
Find the latest guides, application notes, white papers and more for the next generation Octet® SF3 Surface Plasmon Resonance (SPR) platform.
Guides
User Guides
Application Notes
Application Note
Kinetics Determination of High Affinity Molecular Interactions Using OneStep® Injections
PDF | 212.2 KB
Application Note
Kinetic Curvature: Assessment of Small Molecule Kinetics and Affinity Using OneStep® Injections in SPR Screening
PDF | 289.9 KB
Application Note
