Biostat® Cplus
The Stainless Steel Fermenter | Bioreactor for Your Laboratory
The Biostat® Cplus is a Sterilizable-In-Place (SIP) Fermenter | Bioreactor developed for the cultivation of microorganisms and cell cultures. Culture vessels with working volumes of 5 L, 10 L, 15 L, 20 L and 30 L are available. With more than a thousand installations worldwide, the Biostat® Cplus is the most successful stainless steel bioreactor of its class and is now available in the revised 3rd generation with DCU controller.
Top Features
- Choice between electro or steam heating for operation and sterilization; cost-effective integration into existing infrastructure
- Powerful DCU automation platform with newly added functions, e.g. Advanced DO controller, gravimetric feed control and up to four mass flow controllers allowing more sophisticated gassing strategies
- Safe to use due to maintenance-free agitator motor and automatic sequences for sterilization and pressure hold test
- Compact, mobile design saves valuable laboratory space
Ease of Use, Simple Cleaning and a Space-Saving Design
Innovative Technology for Your Process Needs
- Process development and scale-up
- Seed production
Maximum working volumes of (in 2:1 and 3:1 diameter ratio):
- 5 L (benchtop version, only 2:1 ratio)
- 10 L
- 15 L
- 20 L
- 30 L
- O2 Enrichment
- Additive Flow
- Advanced Additive Flow
Advanced DO Controller
In comparison with the conventional DO control cascade, the Advanced DO Controller supports the sequential and parallel operation of up to 5 slave controllers. The controller can be easily configured using the touch screen. Results are graphically displayed as a polygonal curve, which is easy to understand. As a result, you benefit from maximum flexibility for optimal oxygen regulation in your process.
- BioPAT® Trace - Glucose | Lactate measurement
- - Turbidity measurement
- - Off-gas analysis
- - Multi-variant bioprocess monitoring
- Learn more about BioPAT®
- BioPAT® MFCS - SCADA Software
Cell Cultivation
Predictive Cultivation with BioPAT® Sensors
- Control glucose level with the local control software of the Biostat® Cplus
- Automated glucose set point control
- Establish profiles for the glucose concentration set point
- Monitor lactate concentration and display data directly on the DCU screen
- Select up to four variable speed pumps for substrate addition
- Inline monitoring of total biomass based on turbidity
- Inline monitoring of total biomass based on capacitance
Microbial Fermentation
Predictive Cultivation with BioPAT® Sensors
- High precision of gas flow control by intelligent mass flow controllers
- Real-time monitoring of exhaust gas is directly available in your Biostat® Cplus
- Facilitate insights into critical metabolic changes during your fermentation process
- Ensures optimal growth conditions, ultimately increasing the productivity of your process
- Enhanced process parameter control with the help of turbidity measurement
- Greater process understanding of high cell density fermentations
