A Simple Way to Select the Best Antibody-Antigen Pair for Your Lateral Flow Assay

Last updated: September 2023

Overview

Lateral flow assays (LFA) are simple diagnostic tools that can be used to detect a variety of biomolecules that include biomarkers, pathogens, and environmental contaminants. Many industries use LFAs as they are typically rapid assay devices that are especially useful as point-of-care diagnostic devices and as a public health tool that can be sold to users directly. Sartorius is globally recognized a as leading supplier of biotherapeutics and in vitro diagnostics (IVD) solutions. 

Antibodies play a crucial role in the development of LFAs. The quality attributes of these antibodies including the understanding of how they interact with target antigens are essential for the development and optimization of LFAs. The Octet® system is a powerful label-free and easy-to-use high-throughput solution for analyzing biomolecular interactions. In the product development of LFAs, the Octet® system, a Sartorius solution, can be used to investigate antibody-antigen interactions, to perform assay development and optimization and as a reagents quality control tool.


  • Document type: On-demand webinar
  • Watch time: 27 minutes


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Key Takeaways

  • Assay design and considerations in the development of lateral flow assays.
  • Various applications of the Octet® label free systems for biomolecular interactions.
  • How Octet® systems can be used as quality control platforms for the selection of optimal antibodies for the development of lateral flow assays.

This Resource is Designed for:

  • Analytical Lab Assistants
  • Engineers
  • Lab Researchers
  • Assay Developers
  • Quality Control Scientists
  • Scientists

Applications Supported:

  • Lateral Flow Assays (LFA)
  • In Vitro Diagnostics (IVD)
  • Binding Kinetics
  • Antibodies' Quality
  • Antibody-Antigen Interaction

Webinar Speaker[s]

Shuo Liang, Ph.D.

Scientist/Application Specialist

Diagnostic Membrane
Sartorius 

Shuo joined Sartorius in 2020 as a scientist, where she works for the product development and application of diagnostic membranes. She holds a Ph.D. in Biochemistry from Albert Ludwig University of Freiburg. With her experience and knowledge in protein chemistry, Shuo supports the customers to overcome difficulties during the optimization of lateral flow assay development and offers the solution for customers to simplify progress.


The Role of Octet® Systems in LFA Development

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