iQue® Human General Immune Cell Killing Kit
The Human General Immune Cell Mediated Killing Kit was designed for ease of use in multiplexing cellular phenotypic and functional markers and bead-based, secreted cytokine measurements in the same assay. This no wash assay requires minimal hands on time and measures both cells and beads to provide the following biological insights:
- Live immune cells are distinguished from dead cells by staining with fluorescent membrane integrity dye and mitochondrial membrane potential dye.
- Target cells are distinguished from effector cells by staining with a fluorescent encoder dye.
- Simultaneous analysis of multiple mechanisms of immune cell mediated cell killing in a single, high content assay including mitochondrial membrane depolarization, loss of cell membrane integrity, cell count, and pro-apoptotic protease Granzyme B.
Item no.: 97076
Availability: For more information please log in
Speed: Expedient sample to actionable data allows multiple assays to be run in one experiment thereby reducing the hands on time, required numbers of overall tests and conserving precious sample.
Results: Five endpoints from a single well assay measure target and effector cells, mitochondrial membrane depolarization, cell membrane integrity, cell count, and secreted pro-apoptotic protease Granzyme B.
Biological insights: Investigation of multiple mechanisms of immune cell mediated cell killing in one well.
Ease of use: Single platform assay and data analysis with ForeCyt® eliminates the time required for acquiring and correlating data from multiple sources.
Reagents and Kits TypeGeneral Immune Cell Mediated Killing
eShop Dynamic Attributes
ApplicationImmune Cell Function and Characterization
Pack Size1 x 96
- Drug Discovery