Viral Vaccine Cell Culture Media
Specialty Media Designed to Allow Maximum Cell Growth and Infection
Viral vaccines are produced by viral infection of susceptible animal cells or by recombinant protein expression in suitable host cells. A variety of cell lines are used for production of viral vaccines, mostly cells derived from kidneys, such as Vero, MDCK, HEK293 and BHK-21, although others cell types can also be used (sf9, sf21, EB66®, ...). Specialty media offered in this category have been designed to allow maximum cell growth and infection.
BHK-21 Cell Proliferation
The 4Cell® BHK-21 CD Medium is complete medium, ready-to-use, chemically defined, serum-free, animal component-free, antibiotics-free and hydrolysate-free; designed and to reduce costly product purification steps of BHK to support high density growth and maintenance of BHK-21 suspension cell lines used for viral vaccine production.
Superior MDCK Cell Proliferation
4Cell® MDCK CD Medium is a chemically defined, serum-free, protein-free, animal component-free, hydrolysatefree medium designed to the growth and infection of Madin-Darby Canine Kidney (MDCK) cells in suspension conditions, either for research use of for further manufacturing purposes.
Vero Cell Proliferation
The Vero cell line is used for various purposes, most importantly for the production of cell culture-based viral vaccines. Reasons for the extensive use of the Vero cell line are the consistent high viral yields and susceptibility to infect a mutiple range of viruses, as well as relatively easy adaptation for growth in bioreactors on microcarriers, thus allowing up-scaling without loss of cell productivity.
Customized Solutions for Unique Needs
Production-Focused Approach to Produce Your Unique Media Solutions
Perfect choice for clients who have known, desired media composition and outcome expectations. For critical raw materials, you can either request specific suppliers or rely upon Sartorius' established global network of qualified suppliers. Customized packaging, media formats, and release assays are also available upon request.
Explore Our Wide Range of Other Media Suitable for Different Cell Lines
Sartorius's broad range of vaccine cell culture media are used to produce many different viruses including influenza A and influenza B viruses, as well as vesicular stomatitis virus, vaccina, Coxsackie B-5, reovirus types 2, 3 and adenovirus types 4 and 5.